The link between bone disease and cardiovascular complications in hemodialysis patients
Journal Title: Electronic Physician - Year 2016, Vol 8, Issue 6
Abstract
INTRODUCTION: The burden on the cardiovascular system is the main cause of mortality in chronic renal patients, and bone disease, which also may cause disability, is one of the most important complications in those patients. The aim of this study was to determine the link between cardiovascular and bone disease, which frequently occur together. METHODS: In this matched case-control study, 70 subjects were subjected for full laboratory assessment as well as estimation of parathyroid hormone (PTH) level, vitamin D level, complete echocardiography, and dual energy absorptiometry. Of the 70 patients, 50 were on regular hemodialysis, and there were 20 normal controls matched with the patients with respect to age and gender. RESULTS: There was a significant decrease in the mean value of serum vitamin D in the hemodialysis patients, i.e., their mean value was 20.47 ± 9.60 whereas the controls had a mean value of 37.15 ± 7.67. Thus, there was a highly-significant, negative correlation between vitamin D and left ventricular mass (LVM) in the patients. We found that there was a highly-significant increase in the mean PTH levels of the patients (820.22 ± 393.51), whereas it was 57.60 ± 13.72 for the controls. The statistical significance was less than 0.001, a highly-significant increase in the mean of the T score levels in the patients (-2.15 ± 2.56), whereas it was -0.47 ± 0.71 for the controls with a statistical significance of less than 0.001. There also was a highly-significant correlation between the T score and LVM. CONCLUSION: A significant correlation was found between bone disease and the occurrence of a left ventricular mass. We recommend early strict correction of the serum levels of vitamin D, PTH, calcium, and phosphorus
Authors and Affiliations
Elsheikh N, Sherif N, Zeid SA, Eldamarawy M, Ali A, Sabry AI
Keywords
Related Articles
- EP ID EP324435
- DOI 10.19082/2483
- Views 70
- Downloads 0
Corneal transplantation: A new view of life
BACKGROUND: The consequences of a corneal transplant are evaluated and classified by care providers, but understanding and interpretation of the results varies between patients, and creates different views for them and i...
The Impact of Healthcare Reform Plan on the Rate of Vaginal Delivery and Cesarean Section in Shiraz (Iran) in 2015
INTRODUCTION: The uncontrolled increase in the rate of cesarean section is one of the most controversial issues, and is a primary challenge among health policy makers. This study was conducted to examine the impact of th...
Status of antioxidant and homocysteine-lowering vitamins related to cardiovascular diseases in hemodialysis patients
BACKGROUND AND AIM: Cardiovascular disease is the major cause of mortality in hemodialysis patients. Oxidative stress and hyperhomocysteinemia may contribute to an increased risk of CVD. Therefore, we assessed the status...
Correlation between Driver Subjective Fatigue and Bus Lateral Position in a Driving Simulator.
Driver fatigue as a leading cause of death in the transportation industry can impair the driving performance in long-distance driving task. Studies on the links of driver subjective fatigue and the bus lateral position a...
Effectiveness of the mindfulness-acceptance-commitment-based approach on athletic performance and sports competition anxiety: a randomized clinical trial
BACKGROUND: Improving sports performance and reducing anxiety is one of the most important goals of athletes. Recurrence of symptoms and treatment cessation are common problems with common interventions. Approaches based...