The Master Code of Biology: Self-assembly of two identical Peptides beta A4 1-43 Amyloid In Alzheimer’s Diseases
Journal Title: Biomedical Journal of Scientific & Technical Research (BJSTR) - Year 2017, Vol 1, Issue 4
Abstract
Fundamental research published enables us to unify, overall, the genomics and proteomics information of any genetic sequence. This fundamental law is based on a bio-mathematics unification of all genetic information (bio-atoms, nucleotides, codons, amino acids, DNA/RNA/ Proteins) from the level of the six basic bio-atoms C O N H S P to the global level of whole genomes. Concretely, the dynamics of this Genomics/ Proteomics Coupling is appeared as two correlated curves translating topology and the dynamic evolution of a hierarchical classification of codons throughout the studied sequence. More precisely, the study of these curves shows that this tool highlights the functional areas and active sites within proteins. The specific context of Proteins Self-Assembly area could be an interesting field to run and improve our new basic research approach. Particularly, studying Prions by this method we propose a possible Prion PRION self-interaction with a Genomics/ Proteomics correlation coupling ratio of r=99.3 Such prospects oblige us to propose this new theoretical biomathematics approach in the study of the Genetics of the disease of Alzheimer, particularly at the level of Amyloid Plaques
Authors and Affiliations
Jean Claude Perez
Keywords
Related Articles
- EP ID EP571638
- DOI 10.26717/BJSTR.2017.01.000394
- Views 125
- Downloads 0
The Classified Progression in Binding Modes of Autotaxin (Atx) Inhibitors
Autotaxin (ATX) is a secreted enzyme which hydrolyzes lysophosphatidylcholine (LPC) to lysophosphatidic acid (LPA) and choline. The ATX-LPA axis has attracted increasing interest recently for both ATX and LPA are involve...
Device for Detecting Glaucoma
This is a diagnostic device to measure the Intraocular Pressure (IOP) of eyeball, a key indicator for glaucoma. This is a degenerative disease characterized by progressive loss of visual field. According to Glaucoma soci...
Ethno botanical Wisdom of Inhabitant of Devi Galli Azad Kashmir
Plants play vital role in our existence and are major substance of nutrition and medicament throughout the world. Plants are being used from early times to treat various human as well as animal’s diseases. A series of su...
Aristotle: On Intuition and Induction in Research on the Universe
In the ancient Greek culture and philosophy statements about the world had cosmologic and cosmogonic character. The first were totally (like, for example, in Thales’, Anaximander’s, Heraclitus’ philosophy) or partially c...
Why It Is Important to Recognize Brugada Syndrome: A Case Report and Literature Review
Introduction: Brugada syndrome is a rare, but serious clinical entity that is the leading cause of sudden cardiac death in young healthy people. Symptoms associated with Brugada syndrome are caused by re- current ventric...