The Master Code of Biology: Self-assembly of two identical Peptides beta A4 1-43 Amyloid In Alzheimer’s Diseases
Journal Title: Biomedical Journal of Scientific & Technical Research (BJSTR) - Year 2017, Vol 1, Issue 4
Abstract
Fundamental research published enables us to unify, overall, the genomics and proteomics information of any genetic sequence. This fundamental law is based on a bio-mathematics unification of all genetic information (bio-atoms, nucleotides, codons, amino acids, DNA/RNA/ Proteins) from the level of the six basic bio-atoms C O N H S P to the global level of whole genomes. Concretely, the dynamics of this Genomics/ Proteomics Coupling is appeared as two correlated curves translating topology and the dynamic evolution of a hierarchical classification of codons throughout the studied sequence. More precisely, the study of these curves shows that this tool highlights the functional areas and active sites within proteins. The specific context of Proteins Self-Assembly area could be an interesting field to run and improve our new basic research approach. Particularly, studying Prions by this method we propose a possible Prion PRION self-interaction with a Genomics/ Proteomics correlation coupling ratio of r=99.3 Such prospects oblige us to propose this new theoretical biomathematics approach in the study of the Genetics of the disease of Alzheimer, particularly at the level of Amyloid Plaques
Authors and Affiliations
Jean Claude Perez
Keywords
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- EP ID EP571638
- DOI 10.26717/BJSTR.2017.01.000394
- Views 136
- Downloads 0
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