Since the beginning of the human genome project there has been considerable speculation about how this resource and the knowledge creation it enabled would change therapeutic discovery, development, and delivery. As the...
Pharmacogenetics/pharmacogenomics is the study of how genetic variation affects pharmacology, the use of drugs to treat disease. When drug responses are predicted in advance, it is easier to tailor medications to differe...
Our knowledge of the major mechanisms underlying the effect of food on drug absorption allows reliable qualitative prediction based on biopharmaceutical properties, which can be assessed during the pre-clinical phase of...
The purpose of this study was to evaluate the mechanisms of aggregate formation and excipient stabilization in freeze-dried formulations of a recombinant humanized monoclonal antibody. Protein degradation was measured us...
EP ID EP682055
DOI 10.1208/ps0303_commentary3
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How To Cite
Mark J. Dresser (2001). The MDR1 C3435T polymorphism: Effects on P-glycoprotein expression/function and clinical significance. The AAPS Journal, 3(3),
-. https://europub.co.uk/articles/-A-682055
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