The Optimization of Magnetic Resonance Imaging Pulse Sequences in Order to Better Detection of Multiple Sclerosis Plaques
Journal Title: Journal of Biomedical Physics and Engineering - Year 2017, Vol 7, Issue 3
Abstract
Background and Objective: Magnetic resonance imaging (MRI) is the most sensitive technique to detect multiple sclerosis (MS) plaques in central nervous system. In some cases, patients who were suspicious of having MS while having normal MRI images, were questionable whether they do not have MS plaques or MRI images are not enough optimized in order to show MS plaques. The aim of the current study is evaluating the efficiency of different MRI sequences in order to better detect MS plaques. Materials and Methods: In this cross-sectional study which was performed at Shohada-E Tajrish in Tehran, Iran hospital between October, 2011 to April, 2012, 20 patients were included suspected of having MS disease selected by random sampling and underwent routine brain Pulse sequences (Axial T2w, Axial T1w, Coronal T2w, Sagittal T1w, Axial FLAIR) by Siemens, Avanto, 1.5 Tesla system. If any lesion which is suspected to the MS disease was observed, additional sequences such as Sagittal FLAIR Fat Sat, Sagittal PDw-fat Sat, Sagittal PDw-water sat were also performed. Results: This study was performed for about 52 lesions and the results in more than 19 lesions showed that for the Subcortical and Infratentorial areas, PDWw sequence with fat suppression is the best choice, and in nearly 33 plaques located in Periventricular area, FLAIR Fat Sat was the most effective sequence than both PDw fat and water suppression pulse sequences. Conclusion: Although large plaques may be visible in all images, an important problem in patients with suspected MS is screening tiny MS plaques. This study demonstrated that for revealing MS plaques located in the Subcortical and Infratentorial areas, PDw-fat sat is the most effective sequence, and for MS plaques in the periventricular area, FLAIR fat Sat is the best choice.
Authors and Affiliations
Z Farshidfar, F Faeghi, H R Haghighatkhah, J Abdolmohammadi
Keywords
Related Articles
- EP ID EP331751
- DOI -
- Views 72
- Downloads 0
Synergistic Effect of Radiofrequency Electromagnetic Fields of Dental Light Cure Devices and Mobile Phones Accelerates the Microleakage of Amalgam Restorations: An in vitro Study
Background: Previous studies have shown that exposure to electromagnetic fields produced by magnetic resonance imaging or mobile phones can lead to increased microleakage of dental amalgam. Objective: The aim of the pres...
Effects of Plantar Flexor Muscles Fatigue on Postural Control during Quiet Stance and External Perturbation in Healthy Subjects
Background: The maintenance of postural control is a key component in dynamic physical activity, especially during muscle fatigue and against external forces. Despite many studies in this field, there is no consensus reg...
Detection of Ultraweak Photon Emission (UPE) from Cells as a Tool for Pathological Studies
Objective: It is well-known that all living cells emit ultra-weak photon emission (UPE), which is due to byproducts of chemical reactions in cell metabolisms. It has been shown that Reactive Oxygen Species (ROS) in the c...
Parametrization of Pedestrian Injuries and its Utilisation in Proving Traffic Accidents Course Using Injury Signatures and Contact Signatures
Background: The paper points out the present limited possibility of using the verbal description of injuries for the needs of experts from the field of road transportation as relevant criminalistics traces, as well as th...
In-vitro Study of Photothermal Anticancer Activity of Carboxylated Multi-walled Carbon Nanotubes
Background and Objective: Multi-walled Carbon Nano Tubes (MWCNTs) as an important element of nanosciences have a remarkable absorption in the region of NIR window (650-900 nm) which can overcome the limitations of deep t...