The Oxford-Liverpool Inventory of Feelings and Experiences (O-LIFE) schizotypy scale in psychiatry
Journal Title: Archives of Psychiatry and Psychotherapy - Year 2014, Vol 16, Issue 2
Abstract
The aim of this paper is to describe a schizotypy scale, the Oxford-Liverpool Inventory of Feelings and Experiences (O-LIFE), and its use in psychiatry. Schizotypy is a strongly biologically determined personality phenomenon. Schizotypal disorder, as a diagnostic category in contemporary psychiatric classifications, has been included in schizophrenia spectrum disorders. This may reflect similarities in neurobio - logical and neuropsychological features between persons with schizotypy and patients with schizophre - nia. However, schizotypal traits are also more marked in bipolar disorder (BD) compared with those in healthy subjects. The O-LIFE was created by Claridge and his co-workers and consists of four dimensions: unusual expe - riences, cognitive disorganisation, introvertive anhedonia and impulsive nonconformity. Studies using O- LIFE in psychiatry, demonstrated a number of associations between the dimensions of the O-LIFE and the clinical features of schizophrenia, in mood disorders and in healthy persons. In patients with BD treated with lithium carbonate, worse effects of lithium were observed in subjects with high scores on the O- LIFE dimensions (particularly cognitive disorganisation). Recently, some molecular-genetic associations have also been shown between O-LIFE dimensions and polymorphisms of the dopaminergic system and circadian rhythm genes.
Authors and Affiliations
Daria Dembińska-Krajewska, Janusz Rybakowski
Keywords
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