The Population Pharmacokinetics of d -β-hydroxybutyrate Following Administration of (R)-3-Hydroxybutyl (R)-3-Hydroxybutyrate

Journal Title: The AAPS Journal - Year 2016, Vol 18, Issue 3

Abstract

The online version of this article (doi:10.1208/s12248-016-9879-0) contains supplementary material, which is available to authorized users.

Authors and Affiliations

Vittal Shivva, Pete J. Cox, Kieran Clarke, Richard L. Veech, Ian G. Tucker, Stephen B. Duffull

Keywords

Related Articles

Release and permeation kinetics of caffeine from bioadhesive transdermal films

The aim of this work was to investigate, in vitro, the kinetics of release and permeation of caffeine, chosen as model drug, from bioadhesive transdermal films. These films are not self-adhesive but become adhesive when...

Mathematical Model Approach to Describe Tumour Response in Mice After Vaccine Administration and its Applicability to Immune-Stimulatory Cytokine-Based Strategies

The online version of this article (doi:10.1208/s12248-013-9483-5) contains supplementary material, which is available to authorized users.

Structure-Based Prediction of the Nonspecific Binding of Drugs to Hepatic Microsomes

For the accurate prediction of in vivo hepatic clearance or drug–drug interaction potential through in vitro microsomal metabolic data, it is essential to evaluate the fraction unbound in hepatic microsomal incub...

Combined Use of In Vitro Phototoxic Assessments and Cassette Dosing Pharmacokinetic Study for Phototoxicity Characterization of Fluoroquinolones

The present study aimed to develop an effective screening strategy to predict in vivo phototoxicity of multiple compounds by combined use of in vitro phototoxicity assessments and cassette dosing pharmacokinetic (PK) stu...

Pulmonary Immunization Using Antigen 85-B Polymeric Microparticles to Boost Tuberculosis Immunity

This study aims to evaluate immunization with polymeric microparticles containing recombinant antigen 85B (rAg85B) delivered directly to the lungs to protect against tuberculosis. rAg85B was expressed in Escherichia coli...

Download PDF file
  • EP ID EP680876
  • DOI  10.1208/s12248-016-9879-0
  • Views 61
  • Downloads 0

How To Cite

Vittal Shivva, Pete J. Cox, Kieran Clarke, Richard L. Veech, Ian G. Tucker, Stephen B. Duffull (2016). The Population Pharmacokinetics of d -β-hydroxybutyrate Following Administration of (R)-3-Hydroxybutyl (R)-3-Hydroxybutyrate. The AAPS Journal, 18(3), -. https://europub.co.uk/articles/-A-680876