The Potential Role of Store-Operated Calcium Entry (SOCE) Pathways in the Pathophysiology of Epilepsy and Migraine-Like Headaches in Patients with Neurocysticercosis
Journal Title: Journal of Neurology, Neurological Science and Disorders - Year 2017, Vol 3, Issue 1
Abstract
Cysticercosis is the most common helminthic disease of the nervous system in humans. The clinical presentation of neurocysticercosis (NCC) is nonspecific and can mimic a wide array of primary central nervous system (CNS) disorders, making its diagnosis a challenge especially in endemic areas. The pathophysiology of episodic CNS manifestations of NCC is not well understood. We support the hypothesis that mechanisms used by cysticerci to escape the host’s immune system interfere with store-operated calcium entry (SOCE) pathways. This interference may modify brain excitability, leading to episodic manifestations like epilepsy and headaches.
Authors and Affiliations
Fogang Yannick Fogoum, Kamtchum-Tatuene Joseph, Kuate-Tegueu Callixte, Mbonda Paul Chimi, Ndiaye Moustapha, Gallo Diop Amadou
Intratunnel Pressure Measurement in Patients with Carpal Tunnel Syndrome in Vietnam
Objective: Measure the intratunnel pressure of carpal tunnel in patients who underwent surgical treatment for carpal tunnel syndrome in Hanoi Medical University Hospital. Patients and method: Prospective cross-sectional...
Comparison of Serum Soluble Corin Levels among Stroke Subtypes
Background: Serum soluble corin was decreased not only in some cardiac diseases, but also in stroke. Cardiogenic sources play a critical role in ischemic stroke. Serum soluble corin level in stroke subtypes has not been...
Attention-Deficit Hyperactivity Disorder in Childhood Epilepsy
Introduction: Attention-Deficit Hyperactivity Disorder (ADHD) is a recognized cause of learning impairment in children. Several studies have shown that there is an increased prevalence of ADHD in children with epilepsy....
Music Therapy in Patients with Huntington’s Disease: A Case Report
This paper reports about 2 patients with Huntington’s disease who benefit greatly from music therapy while they are struggling with behavioral and emotional problems, due to the advanced stage of the disease. Huntington...
Anterior Tarsal Tunnel Syndrome with Presence of Accessory Deep Peroneal Nerve: Case Report
Entrapment neuropathy of the deep peroneal nerve, also recognized as anterior tibial nerve, typically occurs at the anterior ankle and dorsal foot. Compression of this nerve, which anatomically is inferior to the extenso...