The potential use of gingival crevicular blood from inflammatory and non-inflammatory sites for measuring blood glucose levels: A pilot study
Journal Title: INTERNATIONAL JOURNAL OF CURRENT RESEARCH - Year 2017, Vol 9, Issue 7
Abstract
Introduction: Gingival Probing to assess gingivitis during routine periodontal examination will induce bleeding from the gingival sulcus which can be used to determine the blood glucose level. Objective: To assess gingival crevicular blood glucose levels from inflamed site and non-inflamed periodontal sites and compare it with venous blood glucose and capillary blood glucose levels to check its usefulness as a diagnostic tool. Methodology: According to inclusion and exclusion criteria 100 subjects reporting to the outpatient section of Department Of Periodontology, School of Dental Sciences, KIMSDU, Karad, were enrolled in the study. For all the participants three blood samples were collected for glucose level estimation namely gingival crevicular blood (GCB), finger capillary blood (FCB) expressed by the finger prick method and the Venous blood (VB. For Group A patients (N=50) GCB sample was collected from inflamed gingival units and for Group B patients (N=50) GCB sample was collected from non-inf1amed gingival units. The blood glucose level of the GCB and FCB samples then was evaluated by using glucometer and VB glucose level was estimated by using calorimetric method. Result: GCB Glucose level Values (91%) are closer to the VB Glucose level values as compared to the FCB glucose levels (74%). For group A participants, correlations between VB and GCB glucose readings were high (92%) as compared to the Group B (86%). Conclusion: Within the limitations of this study it can be concluded that gingival crevicular blood can be used for the screening the blood glucose levels And blood glucose levels of the GCB are quite comparable to gold standard laboratory venous blood glucose levels than that of the routinely done finger capillary blood glucose levels. It can also be concluded that inflamed gingival site is preferable over non-inflamed gingival site for screening blood glucose levels during routine dental check-up.
Authors and Affiliations
Dr. Vidhi Bharat Patel, Dr. Vishwajeet Kale, Dr. Girish Suragimath, Dr. Keshava Abbaya, Dr. Siddhartha Varma and Dr. Sameer Anil Zope
Keywords
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