The presentation of laryngeal malignant tumors of mesenchymal origin
Journal Title: Otolaryngologia Polska - Year 2011, Vol 65, Issue 2
Abstract
SUMMARY Although laryngeal malignancies of mesenchymal origin (laryngeal sarcomas, LS) are extremely rare (1% of all laryngeal malignancies), the histological manifestations are very diverse. LS sign as a solid tumor covered with an intact mucosa. The aim of the study: was to evaluate retrospective data referring: epide-miology, clinical manifestations, treatment and early follow-up; based on medical record made in ORL, HNS Surgery Dpt of Holy Cross Cancer Centre in Kielce during 9-years period 2001-2009. Materia! and methods: The retrospective analysis of the group of 12 patients with LS was made. Studied characteristics were: age, sex, primary focus, histological outcome, treatment options and early follow-up. Results: Age of the group of 12 studied patients (10 M, 2 F) ranged from 48 to 84 (mean 69.8). LS accounted 1.2% (12/935) for all of laryngeal malignan-cies. The focus of origin were: glottis (6), epiglottis (5); subglottis (1). The most common histological types of LS at studied group were: neurosarcoma (2), fibrosarcoma (2), plasmocytoma (2), chondrosarcoma (1), malignant fibrous histiocytoma (1), sarcoma low grade (1), lymphoma malignum (1), liposarcoma (1) and haemangioendothelioma epithelioides vel plasmocytoma (1). Methods of treatment were: surgery (6); radiotherapy (1); chemotherapy (1); chemo- and radiotherapy (3); symptomatic treatment (1). The clinical results of treatment are: 9 patients are stili alive (5 pts more than 5 years, 3 pts less than 5 years, 1 pts less than 2.5 years with residual disease); 3 patient died: 2 pts in 1st year from diagnosis, 1 pts after 3 years of treatment died of non-oncological causes. Conclusions: 1. LS are extremely rare and diversed histologically. 2. Immu-nochemical analyses are very important procedures used in diagnostics of these malignancies. 3. An individual approach is needed in diagnostic and therapeutic procedures of LS.
Authors and Affiliations
Stanisław Żyłka , Marcin Zawadzki, Sławomir Okła
Keywords
Related Articles
- EP ID EP52225
- DOI -
- Views 96
- Downloads 0
Results of treatment of 101 otogenic brain abscess — 56-years experience
SUMMARY Introduction: Inflammatory process in the areas of the middle ear creates a possible danger related with the development of extratemporal and in-tratemporal complications. The most dangerous of those include meni...
Malignant mixed tumors of the parotid gland: a review of the Department of Otolaryngology Medical University of Warsaw experience
SUMMARY Objectives: Pleomorphic adenoma (PA), or benign mixed tumor, is the most common salivary gland neoplasm. One of the factors influencing the management strategy in parotid PA is the risk of malignant transformatio...
Sprawozdanie z XLIV Zjazdu Polskiego Towarzystwa Otolaryngologów Chirurgów Głowy i Szyi oraz IV Zjazdu Polskiego Towarzystwa Chirurgów Podstawy Czaszki
Stylalgia – A Missed Diagnosis
Aims and objective: To study the occurrence of stylalgia in patients presenting with pain in the head and neck region and appropriate management options. Materials and methods: This was a hospital-based study. This stud...
Raport z realizacji Programu Powszechnych Przesiewowych Badań Słuchu u Noworodków w Polsce w 2016 roku
Program Powszechnych Przesiewowych Badań Słuchu u Noworodków (PPPBSuN) działa na terenie całej Polski od 14 lat. Jego głównym założeniem jest przeprowadzenie badania przesiewowego słuchu w 2.–3. dobie życia dziecka oraz...