The prevalence of hyperglycemia in critically ill children admitted in PICU
Journal Title: Pediatric Review: International Journal of Pediatric Research - Year 2016, Vol 3, Issue 6
Abstract
Background: Stress hyperglycemia is mainly due to increased gluconeogenesis and glycogenolysis & insulin resistance. Longer duration of hyperglycemia during hospital stay is known to have adverse outcome. Aim of Study: To study the prevalence of hyperglycemia and its association with PICU mortality and morbidity in terms of duration of PICU stay. Design: Prospective Observational study. Method: All critically ill children belonging to age group of 1 month to 14 years, admitted in PICU from 1st May 2011 to 15th September 2011 over a period of four and a half months. Children were followed throughout their hospital stay and outcome in terms of mortality and duration of PICU stay were noted. Blood glucose levels weredone every 3 hourly during the first 48 hours of PICU admission. Highest blood glucose level in the first 48 hours was defined as the peak glucose level. The mean of glucose values of first 24 and first 48 hours were calculated. Result: Prevalence of hyperglycemia was 58%. Mortality rate was higher in the hyperglycemic patients (56%) as compared to normoglycemics (14%) and overall mortality (36%). The p value for difference in the mean of peak RBS and 24 hours mean RBS of the non-survivors and survivors was <0.005 and hence significant. Statistical Analysis: Independent student t test used for analysis. Conclusion: Hyperglycemia during first 24 hours of PICU admission was associated with higher mortality rate and longer duration of PICU stay.
Authors and Affiliations
Hemant Jain, Sunil Arya
Keywords
Related Articles
- EP ID EP225356
- DOI 10.17511
- Views 214
- Downloads 0
A prospective seroepidemiologic study on dengue in children in Southeastern Rajasthan, India
Background: In India, dengue epidemics are becoming more frequent (WHO, 2008). The majority of dengue viral infections are self-limiting, but complications may cause high morbidity and mortality. Objectives: To assess th...
Urolithiasis in a child with acute lymphoblastic leukemia - a case report and review of literature
A two years old girlwith newly diagnosed acute lymphoblastic leukemia on induction chemotherapy developed abdominal colic and passage of powdery material in the urine. Ultrasound abdomen revealed stone in the right kidne...
Cord serum albumin as a predictor of neonatal hyper bilirubinemia in healthy full-term neonates
Introduction: Neonatal jaundice or icterus neonatorum is one of the common problem that is seen in newborns during first week of neonatal life. Clinical jaundice is found in about 80% of preterm and in about 60-70% of te...
Portal vein thrombosis following umbilical vein catheterization in neonates
Objective: To study the association of portal vein thrombosis in umbilical vein catheterized neonates. Study design: Prospective study. Subjects: Neonates in NICU with umbilical vein catheterization. Methods: Doppler ult...
A comparative study of serum electrolytes in newborns with birth asphyxia and non-asphyxiated newborns
Background: Birth asphyxia is a common neonatal problem and contributes significantly to neonatal morbidity and mortality. HIE is the foremost concern in asphyxiated neonate because contrary to other system derangements...