THE PREVALENCE OF METABOLIC SYNDROME IN PATIENTS WITH OSTEOARTHRITIS OF KNEE ATTENDING PHYSICAL MEDICINE AND REHABILITATION DEPARTMENT OF A TERTIARY CARE CENTRE
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2017, Vol 6, Issue 40
Abstract
BACKGROUND Osteoarthritis (OA) is a degenerative joint disease, occurring primarily in older persons. It is the fourth leading cause of Years Lived with Disability (YLD). OA has become a major health problem now; not only because of its increasing prevalence worldwide but also because of its frequent association with cardiovascular disease, the leading cause of death in industrialised countries. There is growing evidence that OA is not simply a disease related to aging or mechanical stress of joints, but rather a “metabolic disorder” in which various interrelated metabolic derangements contribute to the initiation and progression of the disease process. It is a misnomer to label osteoarthritis as a purely degenerative arthritis. It is now clear that an active genetic and proteomic profile suggests inflammation. The cytokine milieu is similarly inflammatory and parallels that found in the Metabolic Syndrome (Met S). Met S is a constellation of metabolic risk factors that directly promotes the development of cardiovascular disease and increases risk for developing Type 2 diabetes. This study is aimed to determine the prevalence of metabolic syndrome in patients with OA knee. MATERIALS AND METHODS It is a descriptive study, which was conducted at Lifestyle diseases management clinic of the Department of Physical Medicine and Rehabilitation, Govt. Medical College, Kozhikode; including 150 subjects with Osteoarthritis of knee as cases and 80 subjects without Osteoarthritis as controls and the prevalence of metabolic syndrome was studied in both these groups. RESULTS The study observed that metabolic syndrome was present in 72% of cases and only in 37.5% among control group. CONCLUSION There is significant association between osteoarthritis of knee and metabolic syndrome (p value of 0.000). The association metabolic syndrome with osteoarthritis of knee was more in females. Among the metabolic profile abnormalities; there was significant association of hypertension with osteoarthritis. The association between hypertension and osteoarthritis of knee was also more among females.
Authors and Affiliations
Anit Antony, Roy Rama Chandran, Abdul Gafoor Shahulhameed, Sonu Mohan Mohanan Sudha, Soumya Viswanath
Keywords
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- EP ID EP213260
- DOI 10.14260/Jemds/2017/686
- Views 81
- Downloads 0
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