The Prevalence of Restless Legs Syndrome in Patients Undergoing Hemodialysis: A Systematic Review and Meta-analysis Study
Journal Title: Basic and Clinical Neuroscience - Year 2017, Vol 8, Issue 2
Abstract
Introduction: Restless legs syndrome is a sensory-motor disorder that causes sleep disorder. The syndrome in patients undergoing hemodialysis has to do with depression, sleep deprivation, performance disorder, day fatigue, excessive daytime sleepiness, stress and anxiety, and increased risk of cardiovascular diseases. The objective of this systematic meta-analysis study was to estimate prevalence of restless legs syndrome in patients undergoing hemodialysis. Methods: Twenty-six articles published between 2000 and 2015 indexed in Iranian (MagIran and IranMedex) and international databases (SID, Google Scholar, ScienceDirect, PubMed, Pre Quest, and Scopus) were selected. Data analysis was carried out through meta-analysis (random effect model) and heterogeneity of the studies was determined using I2 index. The obtained data were analyzed in STAT (11.2). Results: Prevalence of the syndrome according to the articles found and was 50% (95% CI: 38-61) in Iranian and 30% (95%CI: 23-37) in international databases. There was an ascending trend of prevalence of the syndrome corresponding to the publication year of the articles (P = 0.419), while the trend based on age of the patients was descending (P = 0.604); however, the variations were not significant. Discussion: Given the high prevalence and considerable effects of restless legs syndrome on patients undergoing hemodialysis, it is recommended that the patients be screened for the syndrome.
Authors and Affiliations
Reza Ghanei Gheshlagh, Mohammad Farajzadeh, Mozhdeh Zarei, Vajiheh Baghi, Sahar Dalvand, Kourosh Sayehmiri
Keywords
Related Articles
- EP ID EP264671
- DOI 10.18869/nirp.bcn.8.2.105
- Views 122
- Downloads 0
The Impact of Plasmodium Berghei Exposure In-utero on Neurobehavioral Profile in Mice
Introduction: The World Health Organization estimates that about 25 million pregnant mothers are currently at risk for malaria, and that malaria accounts for over 10,000 maternal and 200,000 neonatal deaths per year. The...
Introducing Transthyretin as a Differentially Expressed Protein in Washing Subtype of Obsessive-Compulsive Disorder
Introduction: Obsessive-Compulsive Disorder (OCD) as one of the important mental problems is valuable topic for proteomic research studies to better understand the underlying mechanisms of this disorder. Methods: In thi...
Review Paper: Tau Pathology of Alzheimer Disease: Possible Role of Sleep Deprivation
Sleep deprivation is a common complaint in modern societies. Insufficient sleep has increased the risk of catching neurodegenerative diseases such as Alzheimer’s. Several studies have indicated that restricted sleep incr...
Bone Marrow Stromal Cells With Exercise and Thyroid Hormone Effect on Post-Stroke Injuries in Middle-aged Mice
Introduction: Based on our previous findings, the treatment of stem cells alone or in combination with thyroid hormone (T3) and mild exercise could effectively reduce the risk of stroke damage in young mice. However, it...
Analgesic Effect of 17β-Estradiol on Nucleus Paragigantocellularis Lateralis of Male Rats Mediated Via GABAA Receptors
Introduction: Beside its autonomic functions, the nucleus paragigantocellularis lateralis (LPGi) is involved in the descending pain modulation. 17β-Estradiol is a neuroactive steroid found in several brain areas such as...