THE PROTECTIVE EFFECTS ABELMOSCHUS ESCULENTUS PODS SKIN AND SEEDS AGAINST NICOTINE INDUCED LIVER, KIDNEY DAMAGE IN MICE’
Journal Title: International Journal of Pharmaceutical Sciences and Research (IJPSR) - Year 2019, Vol 10, Issue 6
Abstract
Abelmoschus esculentus is one of the oldest urbane crops grown in many countries and widely distributed. Parts used of okra are fruit, leave seed, root wish showed to have numerous Medicinal significant uses. On the other hand, cigarette, smokers found to have a high a significant effect on liver kidney and other numerous organs in the body. Aim: The study aims to explore the possible protective effects of three parts of okra against nicotine-induced damage in many parts of the mice body. Methods: Fifty male Swiss albino mice were used throughout the study. After tow-weeks acclimatization period, the mice divided into 5 groups from the control group, nicotine-treated group, nicotine-okra pods extract -treated group, nicotine-okra skin extract treated group, and nicotine-okra seeds extract -treated group. Result: shown significant protective effects against nicotine damage effects as cholesterol level decrease in okra skin treatment with a significant difference in comparison with the positive group also okra protective effects on renal function have found that urea and creatinine levels decrease significantly in okra feeding mice. Liver function tests have also been evaluated, and SGPT levels of all okra parts extract have shown significant differences decrease compared to the positive control group. Conclusion: Abelmoschus esculentus possess effects like normalizing cholesterol levels, (antihyperlipidemic roles), suggesting that the consumption of okra may be of benefit in metabolic diseases.
Authors and Affiliations
Mohammed Abdul Muttalib Abdul Bari et al.
Keywords
Related Articles
- EP ID EP580650
- DOI 10.13040/IJPSR.0975-8232.10(6).2739-47
- Views 100
- Downloads 0
THE INFLUENCE OF DIETARY COMPOSITION TO METABOLIC SYNDROME INCIDENCE
Metabolic syndrome is a group of several clinical conditions which is related to the prevalence of another disease such as cardiovascular disease, diabetes mellitus (DM) or increased fasting blood glucose level, visceral...
DEVELOPMENT AND CHARACTERIZATION OF MANNOSYLATED QUERCETIN LOADED LIPOSOMES FOR SKIN CARCINOMA
The solar UV radiation is the major trigger factor that causes skin cancer. Nearly 65% of cases of melanoma occurs dues to high exposure to the UV radiation. It also accounts for 90% of the nonmelanoma skin cancers also...
2D QSAR STUDY OF INDOLE DERIVATIVES AS SELECTIVE COX-2 INHIBITORS
The NSAIDs are popular in reducing acute and chronic inflammation as they have no abuse liability. QSAR (Quantitative structure-activity relationship) approach is a very useful and widespread technique for drug design. 2...
IN-VITRO AND IN-VIVO ANIMAL MODEL FOR SCREENING ANTI-DIABETIC ACTIVITY OF HELLENIA SPECIOSA (J. KOENIG) S. R. DUTTA
Diabetes mellitus is one of the most common endocrine disorder which causes microvascular and macrovascular complications. Herbal medicines derived from plant extracts are used to treat various diseases because of its fe...
“MITREС” AS AN EFFECTIVE DRUG FOR THE TREATMENT OF COWS WITH CHRONIC ENDOMETRITIS
The leading factor restraining the intensification of herd reproduction is endometritis. The article states that the microflora of cow uterine exudate in chronic purulent-catarrhal endometritis is represented by Staphylo...