The Relation of Atopy Status with Response to Treatment in Lung Cancer Patients
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2014, Vol 2, Issue 1
Abstract
The Objective of the study was to identify atopy ratio among lung cancer patients and then compare the response to treatment of lung cancer between atopic and non-atopic groups. Between December 2004 and August 2006; two hundred and one patients, whom were hospitalized and diagnosed as lung cancer, were evaluated by clinical and demographic properties and skin prick test results related to gender, smoking status, cancer cell type-stage and status due to response to treatment. The mean age of lung cancer diagnosed patients was 61.9±0.7. According to histopathologic classification %85 had non-small cell lung cancer and %15 had small lung cancer. In the %13.4 of the patients there was at least one sensitivity to inhalant allergens which were used in skin prick testing. The results of skin prick test on behalf of gender, smoking status, lung cancer type and stage were not significant (p>0.05). One hundred and thirty-six patients, whom were treated with chemotherapy, were evaluated at the end of three months and there was not a significant difference between the responses to treatment according to skin prick test results. There was not a significant relation between skin prick test sensitivity to inhalant allergens which was used as a criteria to asses atopy and response to the treatment of lung cancer. The possible effect of having an atopic status on cancer prognosis could not be claimed. Keywords: Atopy, lung cancer, skin prick test, response to treatment
Authors and Affiliations
Emre Özkan, Bayram METİN, Ayşe Belgin Samurkaşoğlu, Behiye AKKALYONCU BENER
Keywords
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