The role and localization of heat shock proteins in renal cells.
Journal Title: Advances of Science for Medicine - Year 2017, Vol 2, Issue 1
Abstract
Heat shock proteins (HSPs) are important effectors of cellular stress response. They are both pro- and anti-apoptotic factors. Their aim of action is mainly to protection the organizm against harmful effects and regulate the functioning of cellular processes. Unfortunatelly they also contribute to programmed cell death or inflammation in the body. In addition, they are involved in the processes of immune response. These proteins occur in all living organisms. Their concentration decreases with age and increases in the states of illness. Stress factors trigger the simultaneous release of two reactions in the body. One of these reactions allows the cell to survive and the other leads to death. The main feature of kidney damage due to their occlusion or ischaemia is the strong induction of apoptosis in the renal tubule epithelium. The fate of the stressed cell depends on interaction between the mediators of the inflammatory response, the caring proteins and the immune system,
Authors and Affiliations
Małgorzata Skiba, Agnieszka Pedrycz-Wieczorska
Keywords
Related Articles
- EP ID EP230119
- DOI 10.5281/zenodo.1308625
- Views 65
- Downloads 0
Attention deficit hyperactivity disorder
Attention deficit hyperactivity disorder in recent years is one of the most frequently described and diagnosed disorders in school-age children. Among children who cause educational problems, and from early childhood, th...
Peripheral arterial disease as a present health threat
Current predictions indicate that increased life expectancy in peripheral arterial disease in the developed country, including Poland, has been observed. Many risk factors cause morbidity to increase drastically. This in...
Clinical symptoms of menopause
Menopause, according to the definition of the World Health Organization (WHO), is defined as the last natural menstrual bleeding after cessation of which over the next 12 months do not already occurred subsequent bleedin...
Self myofascial release (SMR) at volleyball players
The article presents the method of self-therapy of volleyball players which helps to improve the disposition on the court. There were indicated the benefits of self myofascial release. The basic issues of human physiolog...
Physiotherapy in oncology
The aim of the article is to present a physiotherapeutic approach to cancer. Cancer is the second leading cause of death in Poland. The development of medicine has made us more and more able to analyze the effects of pha...