The Role of Botulinum Toxin A in Treatment of Temporomandibular Joint Disorders: A Review
Journal Title: Journal of Dentistry, Shiraz University of Medical Sciences - Year 2017, Vol 18, Issue 3
Abstract
Temporomandibular joint disorders (TMDs) usually present with symptoms and signs such as pain, mandibular movement, dysfunction, or joint sounds. Botulinum toxin type A (BTX-A) is a biologic toxin which inhibits skeletal muscle through hindering the production of acetylcholine in the nerve endings. This toxin is used for the treatment of hyperactivity of lateral pterygoid muscle and TMD symptoms. This comprehensive review aimed to evaluate the effect of BTX-A injections in the lateral pterygoid muscle on treatment of TMDs symptoms. In this study, online databases including Scopus, Medline, Ebsco, Cochrane, EMBASE, and Google scholar were searched for the keywords “pterygoid muscle” and “Onabotulinumtoxin A”. Twenty-four articles were eligible to be enrolled in the study. In 4 interventional studies and 20 descriptive studies, BTX-A was used for the treatment of TMDs. The dosage and number of injections were different in each study; however, the injection methods were relatively similar. Regardless of the type, number of injections, and dosage, injection of BTX-A in lateral pterygoid seems effective in reducing the click sound and other TMJ-related muscle disorders such as pain, hyperactivity, and dysfunction.
Authors and Affiliations
Rana Ataran, Ayla Bahramian, Zahra Jamali, Vahid Pishahang, Homayoon Sadeghi Barzegani, Parvin Sarbakhsh, Javad Yazdani
Keywords
Related Articles
- EP ID EP239920
- DOI -
- Views 79
- Downloads 0
Tapia’s Syndrome after Cosmetic Malar Augmentation: a Case Report
Tapia’s syndrome is an infrequent complication of airway manipulation. It is usually due to an extra-cranial ipsilateral injury to the hypoglossal nerve and the recurrent laryngeal branch of the vagal nerve, which can ha...
Salivary Chemical Factors in Relation with Oral Cancer in Smokers and Non-Smokers: a Literature Review
Squamous cell carcinoma of oral cavity is of malignant tumors, which causes cancerous complications. DNA damage, mainly because of products of oxidative stress like reactive oxygen species, is a frequent mutagenic that t...
Demographic Evaluation of Oro-Dental Self-Injury for Insurance Deception; Evaluation of the Cases Referred to Shiraz Forensic Medicine Center
Statement of the Problem: Nonsuicidal self-inflicted injuries are socially unacceptable and may cause mild to severe damages. Purpose: This study aimed to evaluate the demographic features of the subjects with orodental...
Diagnosis of Approximal Caries after Delayed Scanning of Photostimulable Phosphor Plates
Statement of the Problem: Considering the high diagnostic accuracy and wide dynamic range of photostimulable phosphor plates (PSPs), they can be a good alternative for radiographic films. Purpose: This study was aimed to...
Comparing Vitamin D Serum Levels in Patients with Oral Lichen Planus and Healthy Subjects
Statement of the Problem: Lichen planus disease is a chronic inflammatory lesion without a known etiology. Recent studies have indicated the role of vitamin D on immune system and proposed its anti-inflammatory effects....