The role of cytomegalovirus in the development of opportunistic infections
Journal Title: Moldovan Medical Journal - Year 2019, Vol 62, Issue 1
Abstract
Background: About one century ago, was found and described a new virus, which, due to its particular way of damaging cells, was called cytomegalovirus. Human is the only natural source of cytomegalovirus infection. The relevance is that it is a widespread pathology, and due to its ability to “disguise” in the human body, remains unnoticed until the “defect” appears in the body’s immune system. It is especially dangerous for pregnant women, children and people with immunodeficiency. It is one of the most common infections that cause pathology in the fetus and newborns, which, in turn, leads to serious consequences, from disability to child death. There are many ways of cytomegalovirus transmission: airborne, parenteral, domestic contact, sexual and vertical (transplacentally, with aspiration of secretions from the birth canal and natural feeding). The virus is able to have a direct and indirect effect on the body. It is able to independently induce immunosuppression. The article describes the epidemiological data, pathogenesis, clinical manifestations, and modern methods of diagnosis, treatment and prevention of cytomegalovirus infection. Also, some diagnostic problems in immunosuppressive organisms are described. Conclusions: Due to its consequences, namely, children`s disability, death and immunosuppressed people, cytomegalovirus has become a demographic problem. A high infection frequency indicates a low level of social development of the population. More public awareness is needed on the transmission and possible consequences of cytomegalovirus infection.
Authors and Affiliations
Elena Cirjau, Emilia Behta
Keywords
Related Articles
- EP ID EP585127
- DOI 10.5281/zenodo.2590026
- Views 185
- Downloads 0
The assessment of different tuberculosis-related features in Moldova regions
Background: Tuberculosis represents a social-related disease and for identifying the priority interventions for reducing its impact must be identified the main disparity features of patients. Material and methods: Global...
Cutaneous leishmaniasis
Background: Leishmaniasis is a disease caused by parasites of the Leishmania type. Cutaneous leishmaniasis is a neglected worldwide, zoonotic, vectorborne, tropical disease. The clinical spectrum of leishmaniasis ranges...
The reevaluation of the role of duodenal dysmotility in the etiopathogenesis of vesicular cholelithiasis
Background: Gallstone disease and chronic calculous cholecystitis are the most prevalent gastro-enterological diseases requiring a surgical treatment. This disease occupies a special place in the pathology of the hepato-...
Anatomic peculiarities of cervix uteri ligaments in pre- and postnatal human ontogenesis
Background: Uterus and uterine cervix ligament concept is a decisive factor for female pelvis surgery and for fundamental mechanisms of urogenital dysfunction ascertainment. According to publications, there are contradic...
Fundamental aspects of cardiovascular regulation in predisposition to atrial fibrillation
Background: Atrial fibrillation is the most common sustained arrhythmia in cardiology. The structural factors leading to atrial fibrillation are well known, but there should be also regarded the functional factors. In 20...