The role of mast cells in pulmonary infectious diseases
Journal Title: Biomedical Transformation - Year 2020, Vol 1, Issue 1
Abstract
Pulmonary mast cells are mainly distributed in the surrounding of pulmonary vessels, bronchi, and mucosa. When pathogens invade, they are directly phagocyted by mast cells through endocytosis. In addition, pulmonary mast cells participate in the antigen presentation of pathogens, and then mediate cellular and humoral immunity. In conclusion, mast cells play an important role in protecting lung from pathogen infection.
Authors and Affiliations
Liu Chao, Xu Feng
Targeting pericyte-expressed circ_0001186 for the inhibition of diabetes-induced retinal vascular dysfunction
Pericytes play important roles in retinal vascular mature and homeostasis. Their dysfunction is a pathological manifestation in diabetes retinopathy. Circular RNAs have emerged as a class of regulatory RNA tran‐ scripts...
Advances on tumor-associated tertiary lymphoid structures in immunotherapy
Tertiary lymphoid structures (TLS) are ectopic lymphoid structures found in non-lymphoid tissues under chronic inflammatory conditions in recent years. Similar to lymph nodes, TLS primarily consist of B lymphocytes, T ly...
Immune-related pathogenesis of COVID-19 andprevention and treatment strategies
Since the outbreak of Corona Virus Disease 2019 (COVID-19), 2.1% of the world's population has been infected and millions of people have died. COVID-19 has become the most serious public health problem throughout the wor...
Progress of detection and identification for pathogenic Candida species and its enlightenment to biomedical transformation
The incidence of opportunistic fungal infection has been gradually increasing over recent years, especially the high morbidity and mortality of invasive Candida infections in immunocompromised individuals. With the emerg...
Progress of gene therapy based on AAV in hereditary deafness
In the past 20 years, the research about gene therapy on hereditary diseases has been deepening. As a safe vector, recombinant adeno-associated virus (rAAV) viruses are widely used in basic and clinical studies of geneti...