The role of microglia in the progression of glaucomatous neurodegeneration- a review

Journal Title: International Journal of Ophthalmology - Year 2018, Vol 11, Issue 1

Abstract

Glaucoma is a serious leading cause of irreversible blindness worldwide. Reducing intraocular pressure (IOP) does not always stop glaucomatous neurodegeneration and the optic nerve may continue to be damaged in the normal IOP. Microglial activity has been recognized to play essential roles in pathogenesis of the central nervous system (CNS) as well as retinal ganglion cell (RGC) survival. The relationship between the neurodegeneration and the microglia cells in glaucoma is very complicated and still remains unclear. In the present review, we summarize the recent studies of mechanisms of microglia in glaucoma neurodegeneration, which might provide new ways to treat glaucoma.

Authors and Affiliations

Jing-Ming Shi

Keywords

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  • EP ID EP497789
  • DOI 10.18240/ijo.2018.01.22
  • Views 49
  • Downloads 0

How To Cite

Jing-Ming Shi (2018). The role of microglia in the progression of glaucomatous neurodegeneration- a review. International Journal of Ophthalmology, 11(1), -. https://europub.co.uk/articles/-A-497789