The Role of Secondary Metabolites on Gynecologic Cancer Therapy: Some Pathways and Mechanisms
Journal Title: Turkish Journal of Pharmaceutical Sciences - Year 2017, Vol 14, Issue 3
Abstract
Gynecologic cancers are among the most common cancers in humans and animals. Treatment success depends on several factors including stage at diagnosis, tumor type, origin and metastasis. Currently, surgery, chemotherapy, and radiotherapy are preferred in the treatment of these cancers. However, many anticarcinogenic drugs can cause severe adverse effects and also the expected response to treatment may not be obtained. In recent studies, the importance of the relationship between cancer and inflammation has been emphasized. Therefore, several phytochemicals that exhibit beneficial bioactive effects towards inflammatory pathways were proven to have anticarcinogenic potential for gynecologic cancer therapy. This review summarizes the role of inflammatory pathways in gynecologic cancers and effective secondary metabolites for cancer therapy.
Authors and Affiliations
Mürşide Ayşe DEMİREL, İpek SÜNTAR
Keywords
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- EP ID EP380976
- DOI 10.4274/tjps.49368
- Views 123
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