The Role of Sexual Dimorphism in the Development of Non-Alcoholic Fatty Liver Disease
Journal Title: Гастроентерологія - Year 2016, Vol 2, Issue 60
Abstract
Metabolic liver disease is often accompanies diseases of various body systems. Non-alcoholic fatty liver disease (NAFLD) — the most common pathology, associated with insulin resistance, diabetes mellitus and obesity. The prevalence of NAFLD varies depending on different factors, among which ethnic origin, age, presence of the metabolic syndrome. The data of recently reported epidemiological studies have shown that hepatic steatosis occurs twice as often in men than in women of childbearing age. It is known that sex hormones are important regulators of lipid exchange and responsible for gender dimorphism of lipid profile. The article presents a review of researches on the role of estrogens in the development of NAFLD at different stages of its pathogenesis: accumulation of fats, inflammation and development of fibrosis.
Authors and Affiliations
V. B. Yahmur, N. V. Nedzvetska, I. S. Kononenko
Keywords
Related Articles
- EP ID EP209983
- DOI -
- Views 73
- Downloads 0
Kariometry Parameters of Hepatocytes on Different Stages of Fibrosis and Portal Hypertension in Patients with Chronic Diffuse Liver Diseases
Thirty three patients have been examined: in two cases in liver biopsy material there was no evidence of fibrosis, 10 persons had stage F1 fibrosis, 10 — F2, 6 — F3 and 5 — F4 in accordance with METAVIR scale. Hepatocyte...
Immunological reactivity in patients with chronic diffuse liver diseases
Background. The aim of the study was to assess the state of the main indicators of cellular immunity and the level of cytokines in patients with chronic diffuse liver diseases (CDLD). Materials and methods. Sixty eight p...
Сomparative Study of Progepar Efficacy in Patients with Non-Alcoholic Steatohepatitis
Non-alcoholic fatty liver disease is one of the most common pathologies of the liver in developed countries. On the average, its prevalence reaches 20 %. In some patients, non-alcoholic fatty liver disease occurs with in...
Functional Dyspepsia in Adults: Diagnosis and Treatment
The objective of the work was to determine the dynamics of clinical symptoms of functional dyspepsia in adults under the influence of treatment using M-cholinolytic (scopolamine butylbromide). We examined 45 patients wit...
New Potential of Non-Drug Treatment of Non-alcoholic Fatty Liver Disease
There are demonstrated the results of the investigation of the course oral use of aqueous solution «Poltava bishofit» in patients with non-alcoholic fatty liver disease. The effectiveness of the proposed non-drug treatme...