THE ROLE OF THYROID HORMONE STATUS IN ABNORMAL UTERINE BLEEDING
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2017, Vol 6, Issue 76
Abstract
BACKGROUND Abnormal uterine bleeding can be defined as any bleeding from the genital tract, which is a deviation from the normal in frequency, cyclicity or quantity. The differential diagnosis of abnormal uterine bleeding includes organic causes that may be subdivided into reproductive tract disease, iatrogenic causes and systemic disease. Thyroid dysfunction is one of the causes included in the systemic diseases. This study was done to know the prevalence of thyroid dysfunction in women presenting with abnormal uterine bleeding. MATERIALS AND METHODS 227 women attending gynaecology outpatient department in Government Medical College, Thrissur, with abnormal uterine bleeding in pubertal to pre-menopausal age group were included in this study after excluding structural and endometrial pathology by clinical examination, ultrasound and endometrial sampling. These women were tested for their thyroid function by FT3, FT4 and TSH estimation in the serum. Patients who were on hormonal treatment, intrauterine contraceptive device users and had bleeding disorders were excluded from the study. Pattern of bleeding was also assessed in the study population. Patients diagnosed with thyroid dysfunction were treated and followed up for the response. RESULTS Out of the 227 patients, the majority of the study population belonged to the age group of 41 - 50 years (43.6%); 21.9% of the study population showed thyroid dysfunction. Of this 19.7% had hypothyroidism, out of which 12.3% were subclinical hypothyroid and 7.5% were overt hypothyroid; about 2.2% were hyperthyroid. Majority of the hypothyroid patients had menorrhagia and majority of the hyperthyroid patients had oligomenorrhoea. CONCLUSION Thyroid hormones play a vital role in menstrual bleeding. Identifying and correction of the thyroid status has shown to improve the symptoms in women presenting with heavy menstrual bleeding and improve the quality of life.
Authors and Affiliations
Lissiamma George, Jacob K. J, Swathi B Shankar
Keywords
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- EP ID EP267478
- DOI 10.14260/Jemds/2017/1182
- Views 98
- Downloads 0
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