The Study of Association of Urogenital Infections as a Risk Factor for Spontaneous Preterm Labour 1Dr.M.S.Sornam, 2Dr.N.Agila Raththi, 3S.Padmanaban
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2017, Vol 2, Issue 6
Abstract
Background Prematurity is the condition where the fetus enters the extra uterine life with biological immaturity. Maturation is defined as the process of completing full development or growth [1]. The embryo and fetus matures intrauterine until organ systems supports the extra uterine life. Thus the degree of maturity is the foremost and main determinant for morbidity and mortality of the neonate. Born too soon babies are more prone for neurological disability, learning disabilities, injury to organs, death, chances of chronic illness and lifetime disability than the term newborns. Since there is no good direct measure for degree of maturity, gestational age calculated during pregnancy is used as a proxy measure of it[1]. Methods After clearance from the hospital ethics committee, this case– control study was undertaken in the Department of Obstetrics and Gynaecology at Kilpauk Medical College and Hospital Chennai from April 2016 to September 2016. Written informed consent was obtained from the women explaining it to them in their language they best understand. Minimum sample size of women with 7 % prevalence of genito urinary infections among antenatal cases not having preterm labor and 30 % prevalence of genito urinary infections among antenatal cases in preterm labor, with a confidence limit of 95 % and a power of 80 was calculated 50 sample size for both study and control groups. Aims & Objectives To find out the association of urogenital infection as a risk factor for spontaneous preterm delivery Results In our study, of the case group 50 women were in 21–30 years of age group and no of women in <21 yrs 60% (30/50) of these were primigravida, multiparous 36% (18/50) and women with previous one abortion is 4% (2/50). In control group of 50 women 48 belonged to 21 to30 yrs age group and 2 of 50 <21 years of age. The control group contained 54% (27/50) of prime gravida, 38% (19/50) were multigravida and 8% (4/50) with previous one abortion. Conclusion I conclude that, in my study, those patients with high vaginal swab positivity are associated with a significant increase in the incidence of preterm labour. In other words vaginal infection was 2.80 times more in women with preterm labor compared to those in control group. And urinary infection is 4 times higher in women with preterm labour compared to those in control group, which indicates a significant association of urogenital infections in preterm labor. Urogenital infections contribute significantly to the preventable causes of preterm labor
Authors and Affiliations
Dr. M. S. Sornam
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