THE STUDY OF CHANGES IN SERUM ELECTROLYTES (Na+, K+, Ca++, Mg++) IN ALUMINIUM PHOSPHIDE POISONING PATIENTS- IS THERE ANY CORRELATION WITH MORTALITY OR SURVIVAL
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 21
Abstract
BACKGROUND Aluminium phosphide (ALP), a solid fumigant pesticide was declared as an ideal fumigant pesticide in 1973 because of its effectiveness, low cost and ease to use. Its toxic effects on humans are due to liberation of toxic phosphine (PH3) gas on contact of moisture and HCL in stomach after ingestion leading to cellular toxicity and death. MATERIALS AND METHODS The present descriptive comparative study comprised of 42 acute aluminium phosphide (ALP) poisoning patients without prior intervention admitted in medical emergency of GSVM Medical College, Kanpur. The details of history and physical examination was recorded, and relevant lab investigations were done. The serum electrolytes were evaluated at the time of admission before any treatment in all the ALP poisoning patients. There were 35 healthy control subjects evaluated for serum electrolytes measurement. RESULTS The study of 42 acute ALP poisoning patients showed hyponatraemia in 30% cases, hypokalaemia in 90%, hypocalcaemia and hypomagnesaemia in 75% each and these changes were statistically significant. The 14 patients who expired had decreased serum Na+ levels in 21.42% cases and in 78.51% cases were having hypokalaemia, hypocalcaemia and hypomagnesaemia each. In the 28 survived patients, hyponatraemia was seen in 42.85% cases, hypokalaemia in 92.85% cases, hypocalcaemia and hypomagnesaemia in 71.43% cases. There was no statistically significant difference between the serum Na+, K+ and Ca++ values of expired and survived patients. However, serum Mg++ level was higher in expired patients than the survived patients, but it was less than the control subjects. CONCLUSION In the study, various significant electrolytes changes were found in the ALP poisoning patients. But as evident from the study, there is no correlation between serum electrolytes levels and mortality or survival of ALP poisoning patients.
Authors and Affiliations
Arvind Kumar, Prem Singh, Tanu Midha
Keywords
Related Articles
- EP ID EP431638
- DOI 10.14260/jemds/2018/581
- Views 76
- Downloads 0
A DESCRIPTIVE STUDY OF INGUINAL HERNIOPLASTY IN A TERTIARY CARE CENTRE
BACKGROUND Hernia may be defined as a protrusion of abdominal viscera outside the abdominal cavity through a natural or acquired defect. Inguinal hernias present with a lump in the groin that goes away with minimal press...
NEVUS LIPOMATOSUS CUTANEOUS SUPERFICIALIS OF HOFFMANN AND ZURHELLE TYPE – A RARE CASE REPORT
PRESENTATION OF CASE A 23-year-old healthy, unmarried female came with complaints of few asymptomatic skin lesions over her left side of back since 12 years of age which progressively increased in size to attain the curr...
A PROSPECTIVE STUDY OF SCALPEL SKIN INCISION VERSUS DIATHERMY IN PATIENTS UNDERGOING INGUINAL HERNIOPLASTY
BACKGROUND Electrocautery is mainly used for haemostasis and less often for skin incisions. We have done a prospective study to compare the postoperative complications regarding skin incisions made by scalpel and electro...
TUBERCULOSIS OF THE PATELLA (A CASE REPORT)
Isolated involvement of patella as extra pulmonary Tuberculosis is very rare. We report a rare case of Tuberculosis patella in an eight year old baby girl. She was complaining of pain, swelling and joint stiffn...
CORRELATION OF TUMOUR PROLIFERATIVE COMPARTMENT, STEROID RECEPTOR EXPRESSION AND GRADE IN INFILTRATING DUCT CARCINOMA OF BREAST
BACKGROUND Hormone receptor evaluation is an important component of breast carcinoma prognostication and is essential for selection of patients for adjuvant chemotherapy. Proliferation is the key for growth and progress...