THE STUDY OF PREVALENCE OF TUBERCULOSIS IN HIV INFECTED AND AIDS PATIENTS AND ITS CORRELATION WITH CD4 COUNT.
Journal Title: International Journal of Advanced Research (IJAR) - Year 2018, Vol 6, Issue 8
Abstract
This study was conducted at Regional Institute of Medical Sciences, Imphal on 50 number of HIV/AIDS patients. Male comprised the majority of the cases (80%) and maximum number of patients were in the age group between 31 ? 40 years of age (44%) with an average age of 33.72 years. The most common route of transmission was intravenous drug use (54%) followed by heterosexual contact (34%). The most clinical features observed were fever > 1 month (68%), weight loss > 10%, body weight (56%), cough (36%), headache (28%), oral thrush and neck stiffness (24%) each and altered sensorium (20%). Co-infection with tuberculosis (TB) was recorded in 52% cases and it was more in patients with lower CD4 cell counts. In cerebrospinal Fluid (CSF) analysis protein was raised in 44% cases and reduced level of sugar was seen in 89% cases. In all the cases increased cell count with lymphocytic predominance was noted. Cryptococcus was detected in 56% cases but no Acid-Fast-Bacilli (AFB) was detected. Histopathological examination of fine needle cytology (FNAC) lymph node showed tubercular lymphadenitis in majority of the cases with positive AFB in few cases. An Extrapulmonary (61%) manifestation of tuberculosis was more than the pulmonary (27%) manifestations and the difference was more with lower CD4 cell counts (≤ 50 cells/cumm). However, the different clinical pattern of tuberculosis in relation to CD4 cell count was insignificant (p>0.05).
Authors and Affiliations
Saru kumar Debbarma, H. Lokhendro Singh, M. Kulachandra Singh
Keywords
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- EP ID EP379649
- DOI 10.21474/IJAR01/7529
- Views 77
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