The substantiation of the parameters of the rotary-film contactor for extracorporeal processing of large volumes of blood using ozone
Journal Title: Праці Одеського політехнічного університету - Year 2017, Vol 1, Issue 51
Abstract
Development and improvement of methods of ozone therapy is closely related to the optimization of the technical tools providing solutions to a variety of clinical applications. Aim: The aim of this research is to develop a new method of extracorporeal ozonation and oxygenation of large volumes of blood, as well as the development of a new type of “ozone – blood” contactor. Materials and methods: The kinetics of the interaction of ozone with whole blood was studied by the "stopped flow" method using a continuous-flow cell. The cell was a rectangular tube formed by parallel glass plates. The cell was located strictly horizontally, filled with the whole blood of the volunteer and thermostated at 37 °C. Ozone-oxygen mixture was blown through the slotted hole along the cell at a controlled velocity. The concentration of ozone was measured with a flow-through photometric analyzer. Results: A comparative analysis of ozone therapy techniques has allowed to develop a new method of extracorporeal ozonation and oxygenation of large volumes of blood. The study of the chemical reaction kinetics of whole blood interaction with the ozone-oxygen mixture made it possible to construct a mathematical model describing the process of the heterophase reaction of ozone-blood interaction in a rotor-film contactor. An experimental copy of the plant for extracorporeal treatment of large volumes of blood with ozone was developed based on the model. The experimental results obtained on the developed hardware-software system showed good correspondence with the theoretical model, thereby confirming the possibility of practical application of the proposed method.
Authors and Affiliations
T. A. Glukhenkaya, V. V. Egorov, N. O. Kanischeva, E. I. Nazarov, A. V. Kipenskiy
Keywords
Related Articles
- EP ID EP316813
- DOI 10.15276/opu.1.51.2017.14
- Views 147
- Downloads 0
Numerical and experimental investigation of heating processes in rubbercord composite un-der cyclic deformation
Composite materials such as elastomers, are widely used in modern engineering. An essential feature of such mate-rials is their viscoelasticity. It’s accompanied with the release of energy as a heat. The self-heating pro...
The role of ecological safety in ergonomics development
The problem of a necessity of application of ecological safety aspects for increasing of ergonomics decisions effectiveness is considered. Actuality of the marked problem is conditioned by the presence of close intercomm...
Free vibration analysis of beams on a Pasternak foundation using Legendre polynomials and Rayleigh-Ritz method.
A free vibration of Euler-Bernoulli and Timoshenko beams resting on a two-parameter elastic foundation of Pasternak type has been investigated. Rayleigh-Ritz method is employed to deduce the governing equation and the Le...
Improvement of the combustion process of diesel engine fuel
To solve the problem of converting fuel energy in the diesel engine in order to increase its efficiency, it is necessary to create additional conditions for the turbulence of the working mixture. It is proposed to introd...
The properties of time-frequency localization of basis functions used in OFTDM communication systems
This article investigates the properties of time-frequency localization (TFL) of various basis functions, such as rectangular function, the function of half cosine, isotropic orthogonal transform algorithm (IOTA) functio...