The Therapeutic Effects of Stem Cell Enhancer on Changes of Some Physiological Parameters in Male Albino Rats Treated With Mixture of Food Additives )Food Preservative, Food Coloring Agent, and Flavor Enhancer)
Journal Title: The Egyptian Journal of Hospital Medicine - Year 2017, Vol 67, Issue 0
Abstract
Background: food additives are substances intentionally added to food to change its characteristics, to maintain and improve safety, to improve or maintain the nutrient value and to improve taste, texture, and appearance. Sodium nitrite is an inorganic salt with widespread applications in the food industry as a food preservative in meat and fish. However, Annatto is used as a dyeing agent in the food industry in coloring butter, cheese, and ice-cream whereas Monosodium Glutamate (MSG) is one of the most used flavorenhancers which is ingested as part of commercially processed foods. Stem cell enhancer is a natural stem cell mobilizer that can trigger the release of millions of adult stem cells from bone marrow into the circulation, and its considerable safety allows for a sustained oral daily intake over long periods of time. Aim of the work: this study was aimed to determine the therapeutic effects of Stem Cell Enhancer (SCE) against the hazardous effects of sodium nitrite, annatto and monosodium glutamate on some physiological parameters in male albino rats. Materials and methods: this study had been done on thirty male albino rats with an average body weight 120-140 g. The animals were divided into three groups; Group 1: control (untreated group), Group 2:rats treated with food additives mixture (sodium nitrite, annatto, and monosodium glutamate); Group 3: rats treated with food additives mixture, in addition to Stem Cell Enhancer. Blood samples were collected, and the separated sera were used for estimation of some biochemical parameters (liver enzymes, kidney functions, glucose, protein profile and lipid profile) and hormonal levels [testosterone,triiodothyronine (T3) and thyroxine(T4)]. Results: the biochemical results showed an increase in the activities of liver enzymes [aspartate aminotransferase (AST) and alanine aminotransferase (ALT)], and the levels of glucose, kidney functions (urea, and creatinine), lipid profile [total cholesterol, triglycerides, low-density lipoprotein(LDL-c), high-density lipoprotein(HDL-c)and risk factors 1& 2] and thyroid hormones [T3 and T4]in the mixture accompanied by a significant decrease in protein profile (total protein, albumin and globulin), HDL-and testosterone hormone levels as compared to the control rats. On the other hand, these results turned back to nearly to the normal values after receiving the Stem cell Enhancer. Conclusion: the present study clearly revealed thetherapeutic capability of SCE to fight the grievous effects of food additives mixture on major physiological parameters.
Authors and Affiliations
Eman G. E. Helal1; ,Rasha A. A. El-Sayed1; GomaaMostafa- Hedeab2; Mariam S. El-Gamal1
Keywords
Related Articles
- EP ID EP499459
- DOI -
- Views 95
- Downloads 0
Melanoma Awareness and self-examination Practices in Saudi Arabia
<strong>Background: </strong>Althoughmelanoma rationalizes less than 1% of cases with skin cancer, it accounts for the greater number of skin cancer deaths. <strong>Objectives: </strong>The objective of this study was to...
Correlation between Central Venous Pressure and the Diameter of Inferior Vena Cava by using Ultrasonography for the Assessment of the Fluid Status in Intensive Care Unit Patients
<strong>Background:</strong> decisions regarding fluid therapy, whether in the operating theatre, intensive care unit, emergency department, are among the most challenging and important tasks that clinicians face on a da...
Role of Medical Imaging in Cases of Stress Urinary Incontinence
<strong>Background:</strong> traditional methods for evaluation of women with urinary incontinence include urodynamic studies with measuring the pressure in the abdomen, the bladder, and the urethra and urine flow analys...
Multiple Myeloma: A retrospective Analysis of the Patients Treated at Ain Shams University Clinical Oncology Department with a Review of the Literature
<strong>Background: </strong>multiple myeloma (MM) is a malignant neoplasm of plasma cells that accumulate in bone marrow leading to bone destruction and marrow failure. Multiple myeloma accounts for about 1.8% of all ca...
Uses of Ultrasound and Doppler in Assessment of Endometrial Receptivity in Patients of Unexplained Infertility
Background: although the majority of infertile couples was found to have an identifiable male or female factor, 15–30% was categorized as having ‘‘unexplained infertility’’. The endometrium is considered to be a key dete...