The Trabecular Meshwork: A Basic Review of Form and Function

Journal Title: Journal of Ocular Biology - Year 2014, Vol 2, Issue 1

Abstract

Glaucoma is a group of optic neuropathies in which damage to the optic nerve results in a distinctive pattern of irreversible vision loss. Elevations in the intraocular pressure (IOP) are a common contributor to this damage. This major cause of blindness affects mainly the elderly population. Over 70 million people are diagnosed with glaucoma worldwide and over 4 million have lost vision in both eyes. The overall prevalence of open angle glaucoma is estimated to be 3.54%.

Authors and Affiliations

Mary J Kelley

Keywords

Related Articles

Upregulation of GADD45α, TP53 and CASP3 mRNA Expression in the Rat Lens after In vivo Exposure to Sub-threshold Dose of UVR B

Purpose: The objective of the present study was to investigate the evolution of mRNA expression of the stress sensor GADD45α, the apoptosis initiator TP53 and the apoptosis executor CASP3 in the rat lens after in vivo ex...

Regulation of Adherens Junctions in Trabecular Meshwork Cells by Rac GTPase and their influence on Intraocular Pressure

Intercellular adherens junctions and cell-extracellular matrix interactions are presumed to influence aqueous humor (AH) drainage via the conventional route, however, their direct role in modulation of intraocular pressu...

Mitochondrial Dynamics in Retinal Ganglion Cell Axon Regeneration and Growth Cone Guidance

Failed axon regeneration and retinal ganglion cell (RGC) death after trauma or disease, including glaucomatous and mitochondrial optic neuropathies, are increasingly linked to mitochondrial dysfunction. Mitochondria are...

Limbal Stem Cells and Corneal Epithelial Regeneration: Current Status and Prospectives

The clear cornea functions like a window that controls the entry of light for visual information and plays a protective role. The failure of appropriate repair following corneal injury results in loss of corneal function...

Review of Inflammation and Infection in Contact Lens Wearers: Risk Factors and Association with Single Nucleotide Polymorphisms

Inflammatory corneal complications associated with contact lens (CL) wear range from self limiting sterile corneal infiltrative conditions such as infiltrative keratitis (IK), and contact lens-induced acute red eye (CLAR...

Download PDF file
  • EP ID EP197787
  • DOI 10.13188/2334-2838.1000017
  • Views 115
  • Downloads 0

How To Cite

Mary J Kelley (2014). The Trabecular Meshwork: A Basic Review of Form and Function. Journal of Ocular Biology, 2(1), 1-9. https://europub.co.uk/articles/-A-197787