Abstract

Background: Staphylococcus is an important pathogen for humans, which is found on skin, mucous membranes and oropharynx of healthy individuals. The bacteria can cause a range of infections from simple wounds and skin abscesses to severe infections such as pneumonia, septicemia, osteomyelitis and endocarditis. Unfortunately because of emerging drug resistance, infections caused by this organism are difficult to treat and may be a leading cause of mortality. This study was aimed to assess the pattern and trend of resistance in Staphylococcus aureus in a referral hospital Shahid mohammadi hospital at Bandar abbas, South of Iran. Method: A prospective cross-sectional study was designed from 2009-2014 on 406 strains of Staphylococcus aureus isolated from patients admitted to a referral hospital in south of Iran. The samples were collected from urine, wounds, ear discharge, burn wound, throat, tracheal secretions, abscess and joint fluid. Antibiotic susceptibility pattern was tested by disc diffusion. The results were analyzed with SPSS 21, using descriptive statistics. Results: Of the collected isolates, 63% were from Men and 37% were from Women. Mean age of the patients was 35 Years. Highest resistance rate was observed for Amoxicillin (88.6%) and lowest resistance was identified for Ciprofloxacin (19.9%). Conclusion: Emerging of multidrug resistance is alarming among Staphylococcus aureus in south of Iran. The abundance of antibiotic prescription and antibiotic sensitivity pattern should be considered because The antibiotic sensitivity varies in different times and different regions. Necessary measures should be taken. appropriate patient treatment and planning should be designed to control and reduce the resistant species, morbidity and mortality associated with MRSA infections.

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