The Trend of Colorectal Cancers at Korle-Bu Teaching Hospital: A Retrospective Histopathological Study
Journal Title: Journal of Cancer and Tumor International - Year 2016, Vol 4, Issue 1
Abstract
Background: Colorectal cancers (CRCs) are common malignancies in Ghana. The aim of the study was to describe the trend and the clinico-pathological characteristics of CRCs in our institution by a retrospective study. Materials and Methods: This was a retrospective study in the Department of Pathology, from January 2002 to December 2012. Results: A total of 521 (50.1%) out of 1,040 gastrointestinal malignancies diagnosed during the period of study period were CRCs. Total of 100 (19.2%) of the patients were less than 40 years old. Many (53.2%) were females. The great majority (93.9%) of the patients had stated symptoms at presentation of which 37.8% were bleeding per rectum. About half (50.0%) of the CRCs were diagnosed in small mucosal biopsies. Approximately 60.8% of the patients reported to a health facility after 3 month of onset of symptoms. Majority (62.2%) of the cancers were located on the left side of the colon particularly the rectosigmoid region (57.4%). The five common CRCs diagnosed in this study were: Conventional adenocarcinoma (80.8%), mucinous adenocarcinoma (6.9%), signet ring adenocarcinoma (3.8%) lymphomas (2.1%) and GIST (1.3%). Of the 199 cases that had Duke’s staging, 40.7% were stage C. Conclusion: There was a rise in the mean age at diagnosis and the number of colorectal cancers over the period of study. Close to 19.2% of the cancers were patients younger than 40 years. Patient presented late with symptoms of advanced disease, most being in Duke’s stage C.
Authors and Affiliations
E. M. Der, R. K. Gyasi
Keywords
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- EP ID EP243388
- DOI 10.9734/JCTI/2016/24745
- Views 64
- Downloads 0
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