The Use of Exosomes in Clinical Applications, With an In-Depth Look at Those Derived From Mesenchymal Stem Cells and Their Use in Myocardial Regeneration
Journal Title: International Journal of Innovative Research in Medical Science - Year 2017, Vol 2, Issue 9
Abstract
Many mesenchymal stem cell (MSC)-based clinical trials are targeted toward cardiovascular diseases, specifically cardiac ischemia. Investigatory work has revealed that MSC-produced “exosomes” are in fact the element that initiates tissue restoration. This, in addition to the advantages of using exosomes over transplanting whole cells, makes “MSC-exosome-based therapy” a very appealing concept. This review will discuss exosomes and their possible clinical applications, with particular emphasis on MSC-derived exosomes and their use in managing ischemic myocardial damage
Authors and Affiliations
Batla Al-Sowayan
Keywords
Related Articles
- EP ID EP450269
- DOI -
- Views 100
- Downloads 0
Locally Applied FK506 Improves Functional Recovery in Rats after Sciatic Nerve Transection
Peripheral nerve injury (PNI) is a serious health concern for society and often causes long lasting disability. Nerve tubulization is recommended when there is too much tension for end-to-end coaptation and the gap betwe...
Hyperlactatemia and Lactic Acidosis Results in Longer Stay in Intensive Care Units (ICUs) and Development of Co-morbid in Post-operative Cardiac Surgery Patients
Pathology of Hyperlactatemia and lactic acidosis is convoluted, including tissue hypoxia, pulmonary abnormalities, Ischemic shock, hypohemoglobinemia and generalized an-aerobic conditions. All or any one of these conditi...
Prevalence of Oral Candidasis in Oral Cancer Expansion
Oral cancer is a multifactorial disease and beside with many potentially malignant disorders, chronic oral Candidiasis is rarely but can transfer into oral cancer. Oral Candidiasis includes the exterior of whitish, velve...
Genetic Disorders Preventive Approach & Its Management: An Ayurvedic Review
The genetic disorders are the prime obstacles in the development of human being. The causative factors for these disorders are the improper formation of genotype. There are many causative factors for the derangement of g...
Measurement of Viscosity of Gummy Fibre from Syzygium Cumini Seeds and Its Co- Relationship to the Mobility and Dialysability of Sugar Molecules by In Vitro Dialysis Studies
Aim: 1. Measurement of Viscosity of Gummy Fibre from Syzygium Cumini Seeds and Its Co- relationship to the Mobility and Dialysability of sugar molecules by in Vitro Dialysis Studies. 2. The effect of water soluble gummy...