The Use of Localised Vaginal Drug Delivery as Part of a Neoadjuvant Chemotherapy Strategy in the Treatment of Cervical Cancer
Journal Title: Gynecology and Obstetrics Research – Open Journal - Year 2015, Vol 2, Issue 1
Abstract
Cervical cancer is the third most prevalent cancer in women globally, with 529,000 diagnosis and 275,000 deaths each year. It is especially prevalent in developing countries where approximately 85% of cases arise due to the lack of cervical cancer prevention and control programs. In developed countries, where women have access to resources capable of detecting and treating precancerous lesions, the number of cases is reduced by approximately 80%.1 Cervical cancer can be characterised, depending on how far it has spread, from stage 0 (precancerous), also called Cervical Intraepithelial Neoplasia (CIN), where abnormal cells are found in the innermost lining of the cervix and have the potential to become cancerous, through to stage 4, where the cancer has spread to the bladder, rectum or other parts of the body, such as the lungs. In developed countries, there are currently two methods used to prevent cervical cancer from developing to an advanced stage: (1) the distribution of HPV vaccines that are mainly directed against HPV types 16 and 182 and (2) screening methods, such as Papanicolaou test (Pap smear), which involves the collection of exfoliated cells from the cervix, which are then examined for cellular abnormalities. This enables identification of CIN before they begin to develop into cervical cancer.
Authors and Affiliations
Christopher McConville
Keywords
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- EP ID EP553476
- DOI 10.17140/GOROJ-2-106
- Views 175
- Downloads 0
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