The Utility of Fibrinogen/C-reactive protein Ratio versus D-dimer and Fibrin Degradation Product in Diagnosis of Overt Disseminated Intravascular Coagulation in Intensive Care Unit patients
Journal Title: The Egyptian Journal of Hospital Medicine - Year 2018, Vol 72, Issue 9
Abstract
<strong>Background: </strong>Coagulopathies in ICU are one of the most common complications in ICU. DIC is one of the most threatening coagulopathies in ICU.It is accompanied with high mortality rates in ICU.Early diagnosis of DIC is very important for early intervention for better prognosis.DIC is caused by several pathologies like sepsis, trauma, obstetric causes and malignancies. <strong>Aim of the Work:</strong> to compare between the sensitivity between fibrinogen/CRP ratio and FDP and D-dimer. <strong>Patients and Methods:</strong> After obtaining approval from the medical ethical committee at Ain Shams University, this observational prospective study was conducted at Ain Shams University Intensive Care Units. The study included 70 patients in Demerdash ICU after including patients with ISTH score ≥5. 2 samples were collected from each patient. <strong>Results:</strong> The results were in favor to the classical parameters of diagnosis of overt DIC in comparison with the new parameter of DIC. It showed that D-dimer and FDPs together were more sensitive than fibrinogen/CRP ratio. <strong>Conclusion:</strong> The D-dimer and FDP tests offered the best test panel in the diagnosis of DIC especially in overt DIC due to their high sensitivity.
Authors and Affiliations
Eman Helal
Keywords
Related Articles
- EP ID EP584313
- DOI 10.12816/ejhm.2018.10743
- Views 80
- Downloads 0
Short Term Outcomes of Non-Surfacing Patelloplasty in Primary Total Knee Arthroplasty
Background: The management of the patella during primary total knee arthroplasty (TKA) is controversial. The most common methods of treating the patella in TKA are patellar resurfacing and non-surfacing patelloplasty. Ob...
Review on Dental Implantology
<strong>Aim of the work: </strong>in this review, we tried to show all details about dental implant, its components, types in the market, usage, case selection and diagnosis, indications and contraindications<strong>.</s...
Prevalence of Factors That Can Increase the Risk of Hip Fracture and Its Complications after Surgery
Background: hip fractures are defined as any fracture of the femur between the articular cartilage of the hip joint to 5 cm below the distal point of the lesser trochanter; they can occur at any age, they but are most co...
Relationship Between Corneal Astigmatism and Intraocular Pressure
<strong>Aim of the work:</strong> this study aimed to investigate the relationship between the Intraocular Pressure(IOP) readings measured by Goldmaan Tonometry and the amount of corneal astigmatism in healthy young subj...
Association of Diabetes Mellitus with ABO Blood Groups & Rh with
Studies have observed an association between ABO blood group and risk for obesity. <strong>Objective:</strong> to evaluate the prevalence of DM in various ABO and Rh blood group subjects, and to explore any association b...