The Utility of the Novel Hematologic Parameters for Predicting in Hospital Mortality in Patients with Acute Mesenteric İschemia
Journal Title: Bezmiâlem Science - Year 2019, Vol 7, Issue 4
Abstract
Objective: Acute mesenteric ischemia (AMI) is recognized as a vascular emergency, having high mortality and requiring rapid and efficient and treatment. In this study, we aimed to assess the levels of neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) in patients with AMI and to search for a relationship between the NLR and PLR values and inhospital mortality of patients with AMI. Methods: In total, one hundred and twenty three patients (67 AMI+ and 56 AMI-) were included in this retrospective study. Sixty seven patients diagnosed as having AMI following computed tomography angiography after presenting to the emergency room were included in AMI (+) group. “Receiver Operating Characteristic” analysis was done to determine the optimal NLR and PLR thresholds in diagnosis and inhospital mortality of AMI. Also, univariate and multivariate analyses were made to evaluate the complete blood count parameters affecting the outcomes of patients with AMI. Results: It was found that AMI+ patients had higher neutrophil count than AMI- patients, while the lymphocyte count was significantly lower (p<0.001 p<0.001, respectively). The NLR and PLR values were significantly higher in AMI+patients than in AMI–patients (p<0.001, p<0.001, respectively). In the multiple logistic regression analysis, only NLR and red cell distribution width were identified as independent predictors of inhospital mortality of patients with AMI [Odds ratio (OR)=1.171, 95% confidence interval (CI)=1.020-1.345, p=0.026; OR=1.474, 95% CI=1.028-2.113, p=0.035, respectively]. Although PLR failed to predict inhospital mortality in AMI+ subjects (area under the curve (AUC=0.597, 95% CI=0.459-0.734, p<0.178), NLR level greater than 10.1, measured on admission, predicted inhospital mortality in AMI+ subjects (AUC=0.698, 95% CI=0.570-0.827, p<0.006). Conclusion: Neutrophil-to-lymphocyte ratio is a reliable predictive marker in hospital mortality in patients with AMI.
Authors and Affiliations
Süleyman Sezai YILDIZ, Murat AVŞAR, Gülçin ERCAN, Serhat SIĞIRCI, Gökhan AKSAN, Hakan KİLCİ
Keywords
Related Articles
- EP ID EP675869
- DOI 10.14235/bas.galenos.2018.2738
- Views 190
- Downloads 0
The Value of Magnetic Resonances Imaging in Localized Lipoatrophy
Localized lipoatrophy usually presents as isolated or multiple, atrophic, depressed areas which are commonly found in the proximal part of extremities. We report a case with idiopathic localized lipoatrophy and want to e...
Analyzing the Odds Ratio Via Distribution Function
Objective: The use of cross tables was frequently seen in early literature research in the biostatistics. Furthermore, its importance in many clinical examinations is still evident today. The aim of this study is to inve...
Ultrasonographic Evaluation of Shoulder in Patients with Diabetes Mellitus
Objective: Shoulder degeneration and rotator cuff tears increase with age and become a frequent cause of shoulder pain. Diabetes mellitus (DM) is the most common endocrine disorder causing pathologies in the musculoskele...
Pseudohypoparathyroidism Type Ia with Normocalcemia
Pseudohypoparathyroidism (PHP) is a heterogeneous group of disorder with parathormone target organ resistance, characterized by hypocalcemia, hyperphosphatemia and high blood parathormone (PTH). Typical phenotypic sympto...
Validation and Reliability of the Turkish Premenstrual Coping Measure
Objective: The aim of this study is to evaluate the Turkish validity and reliability of the premenstrual coping measure (PCM) among university students. Methods: The universe of this methodological study consisted of 36...