THE VALUE OF VASCULAR ENDOTHELIAL GROWTH FACTOR IN PATIENTS WITH CHRONIC GENERALIZED PERIODONTITIS ASSOCIATED WITH METABOLIC SYNDROME
Journal Title: World Journal of Pharmaceutical and Medical Research - Year 2019, Vol 5, Issue 1
Abstract
Background: Endothelial dysfunction (ED) is one of the key independent risk factors for the development of diabetes mellitus, inflammatory, autoimmune and tumoral diseases. Purpose: to study the relationship between the expression of vascular endothelial factor and the number of desquamated endothelial cells in patients with chronic generalized periodontitis (CGP) associated insulin resistance syndrome. Methods: 14 practically healthy persons (control) and 72 patients with moderate BPH (24 patients without concomitant diseases, 48 patients with CHP in combination with MS) were examined. Immunoenzymatic methods were used to determine the number of desquamated cells and vascular endothelial growth factor in blood plasma. Findings: In patients with CGP associated MS, an increase in the level of desquamated endothelial blood cells was revealed against a background of a significant increase in the vascular endothelial growth factor, which is caused by dysfunction of the carbohydrate, lipid and hormonal systems.
Authors and Affiliations
Jakhongir Abduvakilov
Keywords
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