Therapeutic effects of two types of interbody fusions on degenerative lumbar spondylolisthesis in the elderly based on spinal pelvic anatomy and lumbar spondylolisthesis mechanics

Journal Title: Chinese Journal of Clinical Research - Year 2024, Vol 37, Issue 1

Abstract

<b>Objective</b> To evaluate the therapeutic effects of oblique lateral interbody fusion (OLIF) and minimally invasive transforminal lumbar interbody fusion (MIS-TLIF) on degenerative lumbar spondylolisthesis (DLS) in the elderly based on spinal pelvic anatomy and lumbar spondylolisthesis mechanics. <b>Methods</b> A retrospective study was conducted on 122 elderly patients with DLS who underwent surgical treatment in Cangzhou Hospital of Integrated Chinese and Western Medicine from April 2020 to March 2022. Fifty-nine patients who received OLIF surgery were as OLIF group, while 63 patients who received MIS-TLIF surgery were as MIS-TLIF group. The clinical data of operation, pre-operation, immediately after operation and 12 months after operation were collected from two groups of patients, including the spondylolisthesis parameters [intervertebral height (DH), local kyphosis angle (SK), lumbar spondylolisthesis rate (SP), spondylolisthesis angle (SA)], lumbar pelvic anatomical parameters [L1 distance between the center of the vertebral body and the perpendicular line of the sacrum (LASD), lumbar lordosis angle (LL), sacral inclination angle (SS), pelvic inclination angle (PT) and pelvic incidence angle (PI)]. Visual Analogue Scale for Pain (VAS) score and the Oswestry Dysfunction Index (ODI) were used to assesse pain perception and lumbar function. <b>Results</b> Compared with the MIS-TLIF group, the OLIF group had shorter operative time, hospital stay and incision length, less intraoperative bleeding and postoperative drainage flow (P<0.01). In immediate period and 1 year after surgery compared to preoperative levels, both groups of patients showed an increase in DH, a decrease in SK, SP and SA (P<0.05), and a significant decrease in LASD and PT, a significant increase in LL and SS (P<0.05), but no significant change in PI (P>0.05); the VAS score and ODI decreased significantly (P<0.05). At the same time point after surgery, the OLIF group had a larger DH and a smaller SK compared with the MIS-TLIF group (P<0.01), and there was no significant difference in other mechanical parameters of spondylolisthesis, lumbar pelvic anatomy parameters, VAS score and ODI between the two groups (P>0.05). <b>Conclusion</b> OLIF and MIS-TLIF have good improvement effects on the spine pelvic anatomy, mechanical parameters of lumbar spondylolisthesis, pain degree, and lumbar function in elderly patients with DLS, and the effects are similar, but when using OLIF, the operation time, hospitalization time, and incision length are shorter, and the intraoperative blood loss and postoperative drainage are less, which has obvious advantages

Authors and Affiliations

LIU Yang, WANG Zhiwei, ZHAO Chong, WANG Yan

Keywords

Related Articles

Research progress in targeted therapy for gastric cancer

Gastric cancer is a common malignant tumor worldwide, and its incidence rate and mortality have always been in the forefront. Most gastric cancer patients in China are diagnosed in the middle or late stages, with an unsa...

Effects of a single epidural injection of low-dose esketamine on perioperative sedation and analgesia during cesarean section

Objective To evaluate the analgesic and sedative effect of single epidural application of esketamine in cesarean section during perioperative period, and analyze the clinical application value of esketamine in cesarean s...

Analysis of risk factors for late postoperative pleural effusion in patients undergoing single-port thoracoscopic lung surgery

Objective To explore the risk factors of late postoperative pleural effusion in patients undergoing single-port thoracoscopic lung surgery, and to provide a basis for the whole-process management of surgical patients. Me...

Preoperative paclitaxel weekly combined with radical gastrectomy for gastric cancer: randomized controlled study

<b>Objective</b> To explore the clinical efficacy of preoperative paclitaxel weekly therapy as neoadjuvant chemotherapy combined with radical surgery for gastric cancer. <b>Methods</b> Using a randomized controlled study...

Molecular characteristics of 14 239 patients with microsatellite instability colorectal cancer

Objective To analyze their molecular characteristics of microsatellite instability (MSI) by sequencing colorectal cancer patients in Sichuan region. Methods Next generation sequencing (NGS) was used to test 14 239 colon...

Download PDF file
  • EP ID EP735809
  • DOI 10.13429/j.cnki.cjcr.2024.01.017
  • Views 40
  • Downloads 0

How To Cite

LIU Yang, WANG Zhiwei, ZHAO Chong, WANG Yan (2024). Therapeutic effects of two types of interbody fusions on degenerative lumbar spondylolisthesis in the elderly based on spinal pelvic anatomy and lumbar spondylolisthesis mechanics. Chinese Journal of Clinical Research, 37(1), -. https://europub.co.uk/articles/-A-735809