Therapeutic Efficacy of Ozone Injection into the Knee for the Osteoarthritis Patient along with Oral Celecoxib and Glucosamine
Journal Title: Journal of Clinical and Diagnostic Research - Year 2017, Vol 11, Issue 9
Abstract
Introduction: Suffering from osteoarthritis is prevalent among elderly patients so the use of intra-articular injection of medical ozone may well be the effective way to relieve their pain. Aim: To evaluate the effect of intra-articular injection of medical ozone given into the knee of the osteoarthritis patients, and to compare it with taking celecoxib and glucosamine orally. Materials and Methods: In the present study, 76 patients suffering from osteoarthritis were randomly assigned into two groups. In the ozone group, 20 ml ozone-oxygen mixture gas concentration of 20 μg/ml was injected into knee articular cavity and each patient took oral celecoxib and glucosamine hydrochloride. Patients in control group only took the celecoxib and glucosamine hydrochloride orally. Pain score and Lysholm knee score were measured prior to the injection (pretreatment) and at one, three, six weeks after the beginning of the treatment (posttreatment). Results: After the treatment, the pain intensity and function significantly improved in the two groups compared with the pretreatment (p<0.05). In the ozone group, three weeks after intervention, the pain score improved significantly when compared with the control group (p<0.05). After the treatment, the lysholm scores increased significantly (p<0.05), but in the ozone group, it improved faster. Conclusion: Intra-articular injection of ozone plus oral celecoxib and glucosamine could significantly decrease pain intensity in patients with mild to moderate Knee Osteoarthritis (KOA), and improve their functional status early than oral celecoxib and glucosamine only.
Authors and Affiliations
xU feng, Li beiping
Keywords
Related Articles
- EP ID EP363484
- DOI 10.7860/JCDR/2017/26065.10533
- Views 30
- Downloads 0
Retained Foetal Bones with Recurrent Vaginal Discharge: A Case Report
Termination of pregnancy or abortion is rarely known to result in retained foetal bones. The presentation of a patient with retained foetal bones may be in the form of secondary infertility, chronic pelvic pain, dysmenor...
Amelanotic Melanoma Arising in Filarial Leg: A Report of a Rare Case
Amelanotic melanoma arising on chronic lymphoedema has not been reported earlier. We reported a case of amelanotic melanoma of right leg developing in a background of chronic lymphoedema of filarial origin in an elderly...
Hair Loss in Paediatric and Adolescent Age Group: A Clinico-Pathological Analysis in a Tertiary Health Care Centre
Introduction: Hair loss in children causes deep distress to both the child and the parent. The most common causes of paediatric alopecia are tinea capitis, alopecia areata, traction alopecia and trichotillomania. Timely...
Is Local Surgical Site Infiltration as Efficacious as Epidural Analgesia in Laparoscopic Low Anterior Resection?
Introduction: Role of epidural analgesia in laparoscopic surgery is questionable. There is paucity of data comparing local surgical site infiltration with epidural analgesia in laparoscopic colorectal resections. Aim: To...
Sinonasal Neuroendocrine Carcinoma in a Young Female – A Case Report
Sinonasal Neuroendocrine Carcinoma (SNEC) is a very rare malignancy which is difficult to differentiate from other nasopharyngeal malignancies due to similar morphological characteristics and small biopsy specimen. We re...