Therapeutic Efficacy of Peritoneal Dialysis in Pediatric Acute Kidney Injury Patients in a Referral Hospital
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 5
Abstract
Background: Acute Kidney Injury(AKI) in children is associated with significant morbidity and mortality. Peritoneal dialysis (PD) is the preferred and convenient treatment modality for acute kidney injury (AKI) in children and hemodynamically unstable patients. Aim :To study the incidence and clinico-etiological profile of paediatric acute kidney injury patients and the outcome following peritoneal dialysis. Study Design: Retrospective observational study done from November 2007 to August 2016. Materials &Methods :All children aged 1day to 18 years of age with clinical symptoms or abnormal laboratory parameters suggesting acute kidney injury were included in the study. Renal failure classified by pRIFLE. The outcome of acute kidney injury following acute Peritoneal Dialysis was studied in 160 children.Data was analyzed by descriptive statistics.Chi square test is used as test of significance. Results : The incidence of AKI in children requiring dialysis is 4.6% (160/3478). Among them children<1yr age – 37 (23.1%), 1 – 12yrs age – 71 (44.3%), 13 - 18yrs age – 52 (32.5%). Male female ratio was 1.71 (101/59). Infections were the most common etiology in 48.7% (78) with highest being malaria. Glomerular diseases were seen in 11.2% (18) and were more common in 1-12 years age group. Treatment of these patients with peritoneal dialysis was highly effective with complete recovereyof AKI in 120 (75%), partial recoverery in 31(19.3%), Death in 9 (5.6%). Conclusions:Infections are most common cause of paediatric AKI with malaria being most common cause among them in our study. Initiation of renal replacement therapy in the form of acute peritoneal dialysis in children with AKI is associated with good outcome and improved survival.
Authors and Affiliations
Sireesha Gunnam, Gullipalli Prasad
Keywords
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- EP ID EP373895
- DOI 10.9790/0853-1705014146.
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