THERAPEUTIC IMPORTANCE OF OLDER GENERATION ANTIBIOTICS ON GRAM NEGATIVE ISOLATES
Journal Title: International Journal of Medical Research & Health Sciences (IJMRHS) - Year 2015, Vol 4, Issue 4
Abstract
Introduction: Drug resistance is a serious medical problem. Indiscriminate use of antibiotics has led to a state where multi drug resistant bacteria have become increasingly prevalent. Therefore regular surveillance of important pathogens and their resistant pattern is mandatory. Aim: To find out prevalence of organisms causing infection and their sensitivity pattern. Material and methods: 676 clinical samples were screened among which 156 Gram Negative(GN) Isolates were processed for their antibiotic sensitivity profile against 12 different antibiotics. Results: Escherichia coli is the most common isolate of 156 gram negative isolates. Among all antibiotics, ampicillin is least sensitive (22%). Antibiotics with good sensitivity are Imipenam, Meropenam (100%), Levofloxacin 94%, Amikacin 89% Ciprofloxacin 79%, Gentamycin 77%. Pseudomonas is 100% sensitive to Amikacin. Conclusion: Antibiotic resistance in our area is still moderate. It is essential to test for older generation antibiotics before deciding on higher antibiotics for treatment which will have a tremendous impact on the treatment as well as cost effectiveness. Regular surveillance helps in implementing better therapeutic strategies.
Authors and Affiliations
B. Lakshmi| Associate Professor, Microbiology, MNR Medical College, Sangareddy, Email: lakshmibapan@gmail.com, M. Swarajya lakshmi| Associate Professor, Microbiology, MNR Medical College, Sangareddy, Rohini| M.Sc, Microbiology, MNR Medical College, Sangareddy
Keywords
Related Articles
- EP ID EP11526
- DOI 10.5958/2319-5886.2015.00166.6
- Views 255
- Downloads 10
Effect of Anti-Cholinergics with Tamsulosin for Treating Benign Prostate Hyperplasia Patients with an Overactive Bladder: A Clinico-Comparative Study
Objective: Overactive bladder (OAB) symptoms are due to detrusor over activity (DOA) which is characterized by involuntary detrusor contractions during bladder flling. It may co-exist with BOO due to benign prostate hyp...
POST VARICELLA ANGIOPATHY- A CASE REPORT
Chickenpox is a common viral illness in children. In most of the immunocompitent children it’s a self-limiting disease and seldom causes complications. Neurological complications are one of the rare complications of...
Clinical Trials in the Therapeutic Application of Embryonic and Adult Stem Cells for Cardiovascular Disease
Cardiovascular disease (CVD) is a leading cause of morbidity and mortality worldwide, representing a group of disorders characterized by loss of cardiac function as a result of irreversible damage to cardiomyocytes whic...
Study of awareness regarding human rights (HR) in patients of chronic kidney disease (CKD): Experience from a tertiary care hospital in Kerala
Health and human rights are closely interrelated and has included in the WHO and UN constitution. India being a member of UN and WHO has incorporated the health and human rights in its constitution. Chronic kidney disea...
Production and Optimization of Alkaline Lipase by a Novel Psychrotolerant and Halotolerant Strain Planomicrobium okeanokoites ABN-IAUF-2 Isolated from Persian Gulf
lipases have many different applications in detergents, cleaners, food industry, pharmaceutical industry, pulp and paper production and leather industry, but the extremophile lipases have more range applications. These...