THERAPEUTIC IMPORTANCE OF OLDER GENERATION ANTIBIOTICS ON GRAM NEGATIVE ISOLATES
Journal Title: International Journal of Medical Research & Health Sciences (IJMRHS) - Year 2015, Vol 4, Issue 4
Abstract
Introduction: Drug resistance is a serious medical problem. Indiscriminate use of antibiotics has led to a state where multi drug resistant bacteria have become increasingly prevalent. Therefore regular surveillance of important pathogens and their resistant pattern is mandatory. Aim: To find out prevalence of organisms causing infection and their sensitivity pattern. Material and methods: 676 clinical samples were screened among which 156 Gram Negative(GN) Isolates were processed for their antibiotic sensitivity profile against 12 different antibiotics. Results: Escherichia coli is the most common isolate of 156 gram negative isolates. Among all antibiotics, ampicillin is least sensitive (22%). Antibiotics with good sensitivity are Imipenam, Meropenam (100%), Levofloxacin 94%, Amikacin 89% Ciprofloxacin 79%, Gentamycin 77%. Pseudomonas is 100% sensitive to Amikacin. Conclusion: Antibiotic resistance in our area is still moderate. It is essential to test for older generation antibiotics before deciding on higher antibiotics for treatment which will have a tremendous impact on the treatment as well as cost effectiveness. Regular surveillance helps in implementing better therapeutic strategies.
Authors and Affiliations
B. Lakshmi| Associate Professor, Microbiology, MNR Medical College, Sangareddy, Email: lakshmibapan@gmail.com, M. Swarajya lakshmi| Associate Professor, Microbiology, MNR Medical College, Sangareddy, Rohini| M.Sc, Microbiology, MNR Medical College, Sangareddy
Keywords
Related Articles
- EP ID EP11526
- DOI 10.5958/2319-5886.2015.00166.6
- Views 280
- Downloads 10
A STUDY ON ASSOCIATION OF SMOKING AND GASTRIC CARCINOMA IN THE RESIDENTS OF WEST BENGAL
Objectives: The aim of the study is to know the association of tobacco intake in the form of smoking and chewing with gastric carcinoma in West Bengal. Materials and methods: Total 28860 patients (smokers and tobacco c...
The Effectiveness of Social Skills Training on Reducing Negative Symptoms of Chronic Schizophrenia
Because of creating serious problems for patients, schizophrenia has gained many attentions. One method to reduce negative symptoms of schizophrenia patients is mental-social approach. Applied method in this study is se...
Changing spectrum of renal disease in HIV
The study was done to evaluate the spectrum of various renal histopathological lesions in patients infected with HIV (Human Immunodeficiency Virus).32 HIV positive patients underwent Renal biopsy over a period of 3 year...
Assessment of clinical probability and death outcome of pulmonary embolism among ICU patients local experience from Saudi Arabia
Pulmonary embolism (PE) is serious event in medical and surgical practice. Many patients are admitted to the intensive care unit (ICU), and Few reports have addressed the outcome of patients with PE. Data were collected...
A STUDY ON NEW PATTERNS OF CERVICAL DEGENERATIVE DISEASE AT A UNIVERSITY HOSPITAL IN WESTERN REGION OF SAUDI ARABIA
Introduction: Degenerative cervical spine disorders are referred to one or more of the following process: decrease in signal intensity of disc, posterior disc protrusion, anterior compression of spinal cord and dura, d...