THERAPEUTIC IMPORTANCE OF OLDER GENERATION ANTIBIOTICS ON GRAM NEGATIVE ISOLATES
Journal Title: International Journal of Medical Research & Health Sciences (IJMRHS) - Year 2015, Vol 4, Issue 4
Abstract
Introduction: Drug resistance is a serious medical problem. Indiscriminate use of antibiotics has led to a state where multi drug resistant bacteria have become increasingly prevalent. Therefore regular surveillance of important pathogens and their resistant pattern is mandatory. Aim: To find out prevalence of organisms causing infection and their sensitivity pattern. Material and methods: 676 clinical samples were screened among which 156 Gram Negative(GN) Isolates were processed for their antibiotic sensitivity profile against 12 different antibiotics. Results: Escherichia coli is the most common isolate of 156 gram negative isolates. Among all antibiotics, ampicillin is least sensitive (22%). Antibiotics with good sensitivity are Imipenam, Meropenam (100%), Levofloxacin 94%, Amikacin 89% Ciprofloxacin 79%, Gentamycin 77%. Pseudomonas is 100% sensitive to Amikacin. Conclusion: Antibiotic resistance in our area is still moderate. It is essential to test for older generation antibiotics before deciding on higher antibiotics for treatment which will have a tremendous impact on the treatment as well as cost effectiveness. Regular surveillance helps in implementing better therapeutic strategies.
Authors and Affiliations
B. Lakshmi| Associate Professor, Microbiology, MNR Medical College, Sangareddy, Email: lakshmibapan@gmail.com, M. Swarajya lakshmi| Associate Professor, Microbiology, MNR Medical College, Sangareddy, Rohini| M.Sc, Microbiology, MNR Medical College, Sangareddy
Keywords
Related Articles
- EP ID EP11526
- DOI 10.5958/2319-5886.2015.00166.6
- Views 294
- Downloads 10
Evaluation of emergency department performance improvement-A systematic review on influence factors
The emergency department as entrance of hospital and in close relationship with other sections of the emergency service providers provides the wide range of services from the stage of acceptance and initial assessment t...
CLINICO-BACTERIOLOGICAL PROFILE OF DIABETIC FOOT ULCER AMONG THE PATIENTS ATTENDING RURAL TERTIARY HEALTH CARE CENTRE
Background: Worldwide diabetic foot is a major medical problem leading to disability and economic instability to family and country. Objectives: To assess the clinical and bacteriological profile of diabetic foot ulcer...
Influence of climatic parameters on the distribution of air pollutants and public health in Annaba (East of Algeria)
This study is destined to show the relationship that exists between atmospheric pollution from automobile origins and the cases of hospital admissions for cardiovascular causes (ACV) and pulmonary infections (AP) in Ann...
Traditional herbal medicine for weight management: A Review
The prevalence of obesity is increasing at an alarming rate in recent years. Many drugs for weight managing are available in the market; however their adverse effects and hazards have not been thoroughly evaluated, ther...
EFFECTIVENESS OF PEER-COUNSELING FOR PROMOTING OPTIMAL COMPLEMENTARY FEEDING PRACTICES AMONG INFANTS BELONGING TO URBAN SLUMS OF DELHI
Background: Promotion of appropriate complementary feeding practices is important in reducing malnutrition in infants and young children. Yet, India has dismal rates of optimal complementary feeding practices which are...