Therapeutic Modalities in Patients with Ischemic Heart Disease
Journal Title: RA Journal Of Applied Research - Year 2016, Vol 2, Issue 11
Abstract
Objective: Analysis of application of contemporary therapeutic modalities in patients with ischemic heart disease (IHD). Background: Acute Coronary Syndrome (Acs) Is One Of A Number Of Syndromes In A Range Of Clinical Manifestations Of Atherosclerosis Of The Coronary Arteries Or Ischemic Heart Disease, Along With Other Clinical Manifestations Such As Angina Pectoris, Chronic Myocardial Infarction, Valvular Disease, And Eventually Cardiac Failure. Access to the management of ischemic heart disease depending on symptoms, functional and anatomical complexity, includes a variety of therapeutic modalities beginning from medical treatment until emergent treatment using percutaneous coronary interventions or aortocoronary bypass surgery. All patients with ischemic heart disease, for the prevention of disease progression and recurrence of cardiovascular events, should be managed by Guideline directed medical therapy (GDMT). The most important groups of drugs are anti-ischemic drugs, antithrombotic (antiplatelet) drugs, anticoagulants and statins. Even revascularization is indicated in patients with IHD and progressive or refractory symptoms, regardless of the management of medicament. In our patient after admission and during hospitalization there was no progression of symptoms. Abrupt cessation and pain relief, rapid return of ST-segment according to the isoelectric line, with optimal pharmacotherapeutic management led to the stabilization of the patient. If there is an occlusion of the coronary artery, the most important is to establish reperfusion as soon as possible. In our patient reperfusion assessment is determined really fast (coronary angiography), and according to the TIMI (Thrombolysis In Myocardial Infarction) levels are classified in the TIMI 2 (there was no thrombotic occlusion of coronary arteries and a partial reperfusion is established). Despite the fact that percutaneous coronary intervention (PCI) is the method of choice in the treatment of ACS, positive effect of antiischemic drug therapy in our patients influenced the decision to cancel the emergency treatment and continue the treatment only by using medical therapy. Conclusion: The initial therapeutic approach by GDMT (Guideline directed medical therapy) for patients with ischemic heart disease (IHD) reduces the progression of atherosclerosis and prevent coronary thrombosis. In patients with ischemia, routine revascularization (with percutaneous coronary intervention or coronary artery bypass graft surgery) plus GDMT improve prognosis and reduce complications and improve quality of life compared to treatment only by using GDMT. The optimal drug therapy, primary and secondary prevention of IHD by the European Society of Cardiology (ESC) guidelines have almost the same prognostic significance as revascularization
Authors and Affiliations
Esad Alibasic
Keywords
Related Articles
- EP ID EP210941
- DOI -
- Views 133
- Downloads 0
Renal Calculi: An Evidence Based Case Study
Very often patients, suffering from renal calculi are reluctant to surgery unless there is much trouble. They look for medical management whether allopathic, homeopathic or ayurvedic, to get rid of it. Literatures show e...
Estimating The Weighting Effect Of Nanoparticles Of Mud-Solids And Formation-Imported-Solids While Drilling.
Nanoparticles impregnation into water-based mud has proven beneficially qualitative in shale oil formation drilling and cost effectiveness in total well drilling budget. Nanoparticles modified drilling mud have further s...
Religion and experience: drivers of microfinance influence on participation of Turkish women in labor force
Turkish labor markets are characterizable by an unexplained phenomenon of low female labor force participation. The rate of this particular phenomenon belongs to lowest ones worldwide. Also, the trend of the female labor...
The Rational for Civil-Military Cooperation as Part of Humanitarian Response
“Although some critics contend that Civil-Military Cooperation is incompatible with humanitarian values, evidence suggests that such cooperation is essential, this paper critically evaluate the rationale for humanitarian...
Strategic Approaches of Controlling Variables in RP-HPLC Method Development and Validation: A Review
High Performance Liquid chromatography is the principal technique in accessing the drug, its various impurities and drug related degradants that can form on synthesis or storage in pharmaceutical products. It results in...