Therapeutic potential of angiogenesis inhibitor mixtures in cancer treatment
Journal Title: RESEARCH AND CLINICAL MEDICINE - Year 2016, Vol 0, Issue 1
Abstract
It is generally understood that improvement of cancer therapies is achieved by the combination of drugs. This approach will improve efficacy, while toxicity and the risk for drug resistance may be decreased. In this review, the efforts on combining drugs for the treatment of two tumor types is highlighted, followed by a description of the challenges that are faced in designing optimal combination therapies.
P53 is unstable during metastatic development of the human breast cancer: A comparison between the primary tumor and lymph node metastasis
Objective. The aim of this study was to highlight p53 expression during metastatic progression of invasive breast carcinoma of no special type (NST) and to evaluate its role in stratifying patients based on molecular cla...
Results of peginterferon alpha-2a treatment in patients with chronic hepatitis B in the Western part of Romania
Objective: Currently there are two major types of antiviral therapy in HBV chronic liver disease: PegInterferon alpha-2a and nucleoside/ nucleotide agents. The aim of this study was to evaluate the response to PegInterfe...
Morphologic changes in the injured anterior cruciate ligament (ACL) correlated with the expressions of protein S100 AND NFAP: Major therapeutic implications or a wrong gateway towards improving ACL reconstruction ?
Objectives: We examined the histoarchitecture of the anterior cruciate ligament [ACL] stumps in different stages of evolution after injury and we analyzed the correlation with the expressions of protein S100 and neurofil...
Cerebellum developmental challenges: From morphology to molecular issues
Introduction: It is known that, throughout the development of the nervous system, the cellular migratory routes are an important part of its expansion; therefore, the cerebellum is ‘sprinkled’ with cellular changes durin...
The general protocol for the S10 technique
Plastination is a process of preservation of anatomical specimens by a delicate method of forced impregnation with curable polymers like silicone, epoxy or polyester resins, with vast applications in medical fields of st...