Thermostable Vaccines: Past, Present and Future Perspectives
Journal Title: Pakistan Biomedical Journal - Year 2018, Vol 2, Issue 1
Abstract
Vaccines stability has a major role in the success of immunization programs and saves millions of lives every year. To stabilize vaccines cold chains are developed for storage and transport, as efficiency of vaccines is hampered if they are not kept under proper temperature. Aluminum is used for making vaccine thermostable. The development of vaccine formulation is a critical part of overall development cycle of approving, testing and producing new vaccines. However, Liquid vaccine formulation is still preferred over dry formulation because of ease in using, packaging and manufacturing. Other approaches have been used to make vaccine thermostable. This study demonstrates those processes, used to develop thermo-sensitive vaccines into thermostable vaccine andalso describes vaccine formulation designing and use of heat shock protein including mHSP70 and mHSP65 to generate innate and adaptive immune response.
Authors and Affiliations
Misbah Farooqui1*, Amir Sultan2and Hassan Ahmed Khan3
Keywords
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- EP ID EP694171
- DOI https://doi.org/10.52229/pbmj.v2i1.26
- Views 162
- Downloads 0
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