Throbocytopenia an Indicator of Malaria in Febrile Patients- A Retrospective Study
Journal Title: Journal of Medical Science And clinical Research - Year 2015, Vol 3, Issue 3
Abstract
Back ground: Malaria is a major health problem in India. It is mosquitoe born protozoal disease caused by parasite of the genus Plasmodium. Various hematological consequences are produced in patients with this infection, out of which thrombocytopenia is the most common. Objective: To analyze thrombocytopenia and its severity in patients infected with malarial parasite. Methods: The prospective study was conducted during the period of November 2013 to December 2014 on 204 patients who were malaria infected. The diagnosis of malaria was done by peripheral smear examination. Platelet count were performed using automated cell counter. Thrombocytopenia was categorized into mild (1,00,000 – 1,50,000/μl), moderate (1,00,000 – 50,000/μl) and severe (less than 50,000/μl). Presence and severity of thrombocytopenia was compared in different types of malaria. Results: In the study group of 204 malaria infected patients, males were 148 (72.55%) and females were 56 (27.45%). In these patients vivax infection was predominant (76.47%) when compared to falciparum (19.61%) infection and mixed infections (3.92%). The analysis of thrombocytopenias in these patients showed that both the vivax and falciparum infected patients had moderate thrombocytopenia in majority cases. Patients with mixed infection showed moderate and severe thrombocytopenia and no case with mixed infection had normal platelet count in these patients. Conclusion: Presence of thrombocytopenia in patients with fever and chills acts as an indicator of malaria infection, though the severity of the thrombocytopenia is not useful for distinguishing the types of malaria.
Authors and Affiliations
Vissa Shanthi
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