THYROID: AN UPDATED STUDY ON THE DIAGNOSIS AND TREATMENT OF HYPER AND HYPO THYROIDISM
Journal Title: World Journal of Pharmaceutical Research - Year 2017, Vol 6, Issue 12
Abstract
According to the World Health Assembly report, about 1.5 billion persons in more than 110 countries are threatened with thyroid disorders. World Health Organization (WHO) estimation also indicates that about 200 million people have goiter. The thyroid’s job is to make thyroid hormones, which are secreted into the blood and then carried to every tissue in the body. Thyroid hormone helps the body use energy, stay warm and keep the brain, heart, muscles, and other organs working as they should. The thyroid gland is the first of the body's endocrine glands to develop, on approximately the 24th day or 3-4 weeks of gestation, but at around 10-12 weeks the thyroid begins to function on its own. Thyroid hormones are involved in regulation of vital body function. In general normal development, growth and reproduction cannot occur without them. Thyroid function disorders can generally be grouped into two classes, namely hyperthyroidism and hypothyroidism. The proper treatment of hyper- and hypothyroidism depends on recognition of the signs and symptoms of the disease and determination of the aetiology. Thyroid hormones, the only known iodine-containing compounds with biological activity, have two important functions. In developing animals and human beings, they are crucial determinants of normal development, especially in the central nervous system (CNS). The thyroid is responsible for production and secretion of the thyroxin (T4) and tri iodothyronine (T3) hormones and calcitonin throughout the body. Thyroid hormones is regulated by the hypothalamic-pituitary-thyroid axis. The hypothalamus secretes thyrotropin releasing hormone (TRH) in a tropic fashion that activates the anterior pituitary to secrete thyroid stimulating hormone (TSH). TSH targets the thyroid and elevates thyroid hormone production. When adequate thyroid hormones are produced and secreted, the anterior pituitary stops secreting TSH via a negative feedback Mechanism.
Authors and Affiliations
Dr. Niraj Gupta
Keywords
Related Articles
- EP ID EP674635
- DOI -
- Views 137
- Downloads 0
SYNTHESIS OF COUMARIN AND THEIR DERIVATIVES WITH THEIR APPLICATINS BY DIFFERENT METHODS
Coumarin is a natural product obtained from mullein (Verbascum spp.), sweet grass (Hierochloe odorata), cassia cinnamon (Cinnamomum cassia) tonka bean (Dipteryx odorata), vanilla grass (Anthoxanthum odoratum) and sweet w...
PREVALENCE OF POLYCYSTIC OVARIAN SYNDROME WITH ASSOCIATED RISK FACTORS AND IMPACT ON WELL-BEING AMONG WOMEN IN REPRODUCTIVE AGED (18-45) YEARS IN AL - MADINAH 2017
Background: Polycystic ovary syndrome (PCOS) is a common endocrine disorder in women worldwide. There a shortage of recent data about its prevalence and epidemiologic features in Saudi Arabia. Objectives: The study aimed...
DESIGN AND EVALUATION OF MUCOADHESIVE BUCCAL BILAYERED TABLETS OF METOPROLOL SUCCINATE
The purpose of this research work was to establish mucoadhesive buccal tablets of Metoprolol succinate in the forms of bilayered tablets. The tablets were prepared using Hydroxy propyl methyl cellulose (HPMC K100M) and P...
METHOD DEVELOPMENT AND VALIDATION FOR THE ESTIMATION OF SAROGLITAZAR IN PHARMACEUTICAL DOSAGE FORM BY RP-HPLC
A simple, sensitive and rapid reverse phase high performance liquid chromatographic method was developed for the estimation of Saroglitazar in tablet dosage form. A C18 Inertsil ODS column (250 × 4.6 mm, 5μm particle siz...
EFFECT OF RESVERATROL ON LIVER DIFFERENTIAL HEPATOCYTES AND KIDNEY HISTOPATHOLOGY ON LEADINDUCED TOXICITY IN WISTAR RATS
The aim of this experiment was to investigate the effect of resveratrol on liver differential hepatocytes and kidney histopathology in leadinduced toxicity in wistar rats. The study employed wistar rats (150 - 200 g) whi...