THYROID DISORDERS IN HIV PATIENTS- A SINGLE CENTRE CROSS-SECTIONAL STUDY
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 16
Abstract
BACKGROUND There is report of increasing prevalence of thyroid disorders in HIV positive patients. Currently, there is insufficient data to recommend routine screening for thyroid disorders in asymptomatic HIV patients; hence, this study was undertaken to resolve these issues. MATERIALS AND METHODS This is a comparative descriptive study of 150 seropositive HIV patients, which was taken for convenience conducted at LLRM Medical College and SVBP Hospital, Meerut, U.P. RESULTS Overt hypothyroidism was found in 3.33% patients, subclinical hypothyroidism was found in 9.33% patients, isolated low FT4 was found in 2.66% patients, while sick euthyroid syndrome was found in 26% patients. None of the patients was found to be having hyperthyroidism. As the disease progressed FT4 and FT3 levels decreased, while TSH level increased. A direct positive correlation between FT4, FT3 and CD4 count was established, while a negative correlation between S. TSH and CD4 count was found. Mean FT3 and FT4 levels were lower in patients on HAART, while mean TSH level was higher in patients on HAART. CONCLUSION Thyroid dysfunction in HIV patients was largely asymptomatic. There was a direct correlation between WHO clinical stage and FT3 and FT4 levels. TSH level increased as CD4 count decreased. Patients on HAART had a higher prevalence of subclinical hypothyroidism.
Authors and Affiliations
Devinder Kumar Vohra, Gaurav Garg, Yogita Singh, Snehlata Verma, Rahul Goel, Alka Srivastava
Keywords
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- EP ID EP414624
- DOI 10.14260/jemds/2018/441
- Views 86
- Downloads 0
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