Thyroid hormones in male reproduction and infertility
Journal Title: Asian Pacific Journal of Reproduction - Year 2019, Vol 5, Issue 8
Abstract
Thyroid hormones have been well studied for its relevance to male reproduction in the last few decades. They are considered as essential regulators of male reproductive functions and play vital roles in male gonadal developments. Hyperthyroidism and hypothyroidism both affect testicular functions and influence neuroendocrine regulations over reproductive functions via the crosstalk between the hypothalamic-pituitary-thyroid axis and the hypothalamic-pituitary-gonadal axis. The alterations in the male reproductive hormonal milieu by thyroid hormones may lead to reduced testosterone levels and deterioration of semen quality. However, there are very few reports on the direct effects of thyroid disorders upon testicular functions and semen quality. This article aims to review the available literature to present a concise updated concept on the regulation of male reproductive functions by the thyroid hormones, and the possible mechanism by which thyroid dysfunctions affects testicular functions.
Authors and Affiliations
Ahmed Alahmar, Sulagna Dutta, Pallav Sengupta
Keywords
Related Articles
- EP ID EP648656
- DOI 10.4103/2305-0500.268135
- Views 167
- Downloads 0
Comparison of serum reproductive hormones, antioxidants, PGE2 and PGF2-α between primary and secondary infertile women in Calabar
Objective: To compare the prolactin, progesterone, luteinizing hormone, follicle stimulating hormone, estradiol, antisperm antibodies, tumor necrosis factor α, total antioxidant capacity, prostaglandin E2 and F2α between...
The methanolic extract of Guibourtia tessmannii (Caesalpiniaceae) improves sexual parameters in high fat diet-induced obese sexually sluggish rats
Objective: To evaluate the effects of the methanolic extract of Guibourtia tessmannii (G. tesmannii) on sperm parameters, lipid profile and testosterone level in obese rats. Methods: A total of 193 male Wistar rats were...
Factors affecting in-vivo fertility of crossbred Egyptian - Italian buffalo semen
Objective: To assess the effect of region, season and year of insemination on in-vivo fertility of Italian-Egyptian crossbred buffalo semen. Methods: A total number of 4 799 female buffaloes were inseminated by frozen se...
Genetic polymorphism and natural fertility in women
Objective: To investigate the cooperative interaction among five genetic systems (phosphoglucomutase locus 1, adenosine deaminase locus 1, acid phosphatase locus 1, adenylate kinase locus 1, and haptoglobin) concerning t...
Improvement of Phaseolus vulgaris on breastfeeding in female rats
Objective: To evaluate effect of Phaseolus vulgaris (P. vulgaris) on the breastfeeding in female rats. Methods: This experimental study was done from May 2018 to December 2018 in the Anatomical Department of Medical Scho...