Thyroid Profile Status of Female Patients with Polycystic Ovary Syndrome (PCOS) in Western Rajasthan
Journal Title: International Journal of Medical Research Professionals - Year 2017, Vol 3, Issue 2
Abstract
Background: Polycystic ovarian syndrome (PCOS) is a common endocrine disorder in women with 6-7% prevalence in the world. PCOS produces symptoms in approximately 5% to 10% of women of reproductive age (12–45 years old). The heterogeneous disorder is associated with menstrual irregularities, hyperandrogenemia, obesity, increased insulin levels and insulin resistance. PCOS together with thyroid disorder create independent risks of ovarian malfunction as well as pregnancy associated problem. An abnormal thyroid concentration could trigger alterations in ovulation and then menstruation. Objective: Assessment of serum Thyroid profile Levels in Female patients with Polycystic ovarian syndrome (PCOS) trying to find a correlation between Polycystic ovarian syndrome (PCOS) and the metabolic functions of Thyroid gland, as well as pregnancy associated problem. Patients and Methods: 50 females were included in this study, they were divided into 2 groups, the first group included 25 PCOS female patients of age group (18-30yr) attending the Out Patient Department, Department of Obstetrics and Gynecology, Dr. S.N. Medical College and its associated group of hospitals, Jodhpur. The result will be compared with the second group in which age matched 25 healthy- control female subjects were included. Patients and controls were subjected to fill history taking, duration of the disease, the clinical course and any complications in relation to the disease were noted, measurement of body mass index and assessment of Serum thyroid hormones and Serum TSH level which was measured by using Enzyme Linked Fluorescent Assay Method. Results: PCOS female patients were found with elevated Serum TSH level and Mean serum TSH values were highly significant as compared to healthy control subjects. While Serum T3 and Serum T4 levels were almost similar in both groups and there was a non-significant relationship. Conclusion: The subclinical higher level of thyroid stimulating hormone in PCOS female patients may be associated with the development of the disease and may also implicated with other symptoms of the disease. As there is high prevalence of thyroid disorders in PCOS patients, thus all women in their reproductive age with and without PCOS, should have their thyroid function tests evaluated.
Authors and Affiliations
Dhamija Shilpa, Kumar Rohitash, Mathur Ranjana
Keywords
Related Articles
- EP ID EP543827
- DOI 10.21276/ijmrp.2017.3.2.025
- Views 69
- Downloads 0
Risk Factors Potentiating Substance Abuse among Saudi Females: A Case Control Study
Introduction: For controlling the substance use issue, it is important to have a good knowledge of risk predisposing an individual towards substance use. The risk factors potentiating substance use among Saudi women are...
Patient Satisfaction with Post Closed Nasal Bone Reduction
Background: A lot of controversy around closed reduction approach of nasal bone fracture when it comes to the most satisfying approach in both functional and cosmetic areas. Objective: To determine the rate of satisfacti...
Histopathological Diagnosis amongst Subjects of Liver Diseases Reporting to the Pathology Department at a Tertiary Care Centre
Background: Chronic liver diseases are one of the greatest cause death around the world, representing around 1.03 million deaths each year. The aim of the present study was to evaluate the histopathological diagnosis of...
Retrospective Evaluation of Infections Occurring in Patients Undergoing Treatment with Locking Reconstruction Plates
Background: The utilization of locking screw plates is viewed as exceptionally supportive specifically in osteoporotic distal femoral fractures, considering their decencies in opposing to various collapses and having num...
Retrospective Analysis of Surgical Outcome in Traumatic Extradural Haematoma: An Institutional Experience
Background: Traumatic extradural hematoma (EDH) has been recognized for more than 140 years. 100 years ago, the mortality rate of EDH was as much as 86% and traumatic EDH remains a true neurosurgical emergency. With the...