Thyroid Status and Serum Protein Levels in Severe and Moderate Acute Malnourished Children
Journal Title: Journal of Medical Science And clinical Research - Year 2016, Vol 4, Issue 1
Abstract
Aims And OBJECTIVES; 1. To estimate and compare blood thyroid hormone levels and proteins in Protein Energy Malnutrition ( PEM ) patients with normal values 2. To find correlation between blood thyroid hormone levels and protein abnormalities in children with PEM and to compare it with normal values. STUDY DESIGN: It was a Prospective Observational Study done at a tertiary care hospital in a metropolitan city over a period of 3 years. This study comprised Of 100 patients who were divided on the basis of WHO staging for PEM into SAM (severe acute malnutrition) and MAM (moderate acute malnutrition) on the basis of weight for height ,height for age ,mid arm circumference and wasting or oedema. Assessment of total Serum Proteins was done with Albumin and Globulin Albumin /Globulin ratio estimation, Thyroid Function test –TSH, Free T3, Free T4 was done. These values were compared in children with PEM and the values were correlated with children with PEM. RESULTS: Serum proteins were low in both SAM and MAM ,the decrease in the serum proteins was more with the severity of malnutrition that is more decrease in SAM and borderline low in MAM ,there was highly significant correlation (p<0.001) between the decreased serum proteins and the type of malnutrition. Serum Free T3 values was low in SAM patients and normal in MAM, showing highly significant correlation (p<0.001) between the decreased Free T3 and the severity of malnutrition. Serum Free T4 values were within normal limits both in SAM and MAM patients, but there was highly significant correlation (p<0.001) between the low value in SAM as compared with MAM patients i.e., the value was less in SAM patients as compared with MAM patients .Serum TSH values were normal in both SAM and MAM patients and there was no correlation between the TSH values and the malnutrition. CONCLUSION: Serum albumin and globulin levels were low along with a decrease in A:G ratio in PEM cases and severity of hypoprotinemia was directly proportional to severity of PEM. Free T3 was decreased indicating that there was low conversion of T4 to T3. There was a direct correlation with the decrease in A:G ratio and decrease in Free T3 and Free T4 values.
Authors and Affiliations
Dr S. K. Valinjkar
Keywords
Related Articles
- EP ID EP213194
- DOI -
- Views 72
- Downloads 0
Maternal and Fetal Outcomes in Previous One Cesarean Pregnancies
A previous caesarean delivery does cast a shadow over the outcome of future pregnancy and labour, main fear being catastrophic uterine rupture. Vaginal birth or trial of labour after previous caesarean delivery has becom...
Tadalafil therapy in symptomatic improvement of LUTS due to BPH and associated Erectile Dysfunction
Introduction: Benign prostatic hyperplasia, one of the most common urological problem in aging man, is a complex disease and is often associated with bothersome LUTS. Objective: The aim of present study was to assess the...
Diabetes and Tuberculosis: The Study of Clinical-radiological Profile in Tertiary Care Hospital
Background - DM is a well known risk factor for TB in the past 1,2. Patient with diabetes mellitus type-2 are in particular more prone to getting into infections, including TB, which are more difficult to treat because o...
A Comparative Study of Ropivacaine with Dexmeditomidine and Fentanyl Spinal Anaesthesia in Uro-Gynacological Surgeries
This study was conducted in 106 adult patients with ASA physical status - planed for lower abdominal uro -gynac surgeries under spinal anaesthesia. We compared the onset & duration of motor and sensory block and time...
Evaluation of Modified Alvarado Score and Ultrasonography for the Diagnosis of Acute Appendicitis at Tertiary Care Hospital in Western Rajasthan
Background: Acute appendicitis is most common cause of pain abdomen. The diagnosis of which remain difficult in many cases. Methods: A 100 consecutive patients suspected of acute appendicitis who were admitted in departm...