TIGECYCLINES: A BRIEF REVIEW
Journal Title: Journal of Biological and Scientific Opinion - Year 2018, Vol 6, Issue 1
Abstract
Tigecycline is a tetracycline derivative of glycylcycline group of antibiotics. It is broad spectrum bacteriostatic antibiotics discovered with aim of fighting havoc of bacterial resistance. Its antibiotic spectrum covers almost all the bacteria including Clostridium diffcile and can be prescribed to immunocompromised patients suffering from cancer. The N,N-dimethyglycylamido (DMG) moiety attached to the 9-position of tetracycline ring D increases its spectrum activity. It falls under the group of protein synthesis inhibitors.
Authors and Affiliations
Sushree Sangita Mohapatra, Arjun Kafle, Sumitra Panigrahi, Subha Ganguly
Keywords
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- EP ID EP650702
- DOI 10.7897/2321-6328.06172
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