Time and Predicting Factors of Non-compliant TB Patients to Default Treatment - A Perspective from Sudan - 2016
Journal Title: International Journal of Contemporary Medical Research - Year 2017, Vol 4, Issue 1
Abstract
Introduction: Tuberculosis is a chronic infectious disease that requiring prolonged course of treatment. The Treatment regimens recommended under Sudan National Tuberculosis Program have shown to be effective, but poor compliance is a major barrier to its management, and a challenge to the TB programs. The overall objective of this article was to identify the time and predicting factors of non-compliant TB patients who default from treatment. Material andMethods: A cross-sectional study was conducted among TB patients registered in Kassala State. The sample size mounted to 366 participants who were selected using simple random sampling technique. A standardized administered, pre-tested and pre-coded questionnaire was used to collect the data. The questionnaire consisted of 10 sections with a total of 80 questions. A multivariate logistic regression analysis model was built using the enter method for the statistically significant variables at univariate analysis level taking P-value of 0.25 to determine the association between default and the study outcomes. Results: 366 TB patients were included in this study, of whom 60 were identified as treatment defaulters. Majority of defaulters 46 (73.7%) discontinued their treatment at the start of the continuation phase (P-value 0.05); and only 14 (23.3%) at the intensive phase. 50 (83.3%) of the defaulters cited that they discontinued their treatment after feeling better (and wrongly perceiving it as cure), which was strongly associated with default, P-value 0.004. Also, 6 (10%) of defaulters attributed their default to drugs side effects. Conclusion: Most of non-compliant TB patients in Kassala state defaulted at the start of continuation phase. Discontinuing treatment after feeling better (and wrongly perceiving it as cure) was found to be the major predictive factor of default from anti-TB treatment. Therefore, additional efforts to improve the compliance of patients with anti-TB treatment through TB patient education, counselling and close follow at the start of continuation phase are extremely important measures to be considered in TB control policy in the future.
Authors and Affiliations
Mohammed Elmuttalut, Mustafa Khidir Elnimeiri
Keywords
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